Evidence map›Paper›PMID 38774915›Full record

ArticleJACC. Advances2024

Cardiovascular and Noncardiovascular Prescribing and Mortality After Takotsubo Comparison With Myocardial Infarction and General Population.

Amelia E Rudd, Graham Horgan, Hilal Khan, David T Gamble, Jim McGowan, Arvind Sood, Ross McGeoch, John Irving, Jonathan Watt, Stephen J Leslie and 5 more

Abstract read
In one paragraph

Article in JACC. Advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Review
  6. Prospective comparison of temporal changes in myocardial function in women with Takotsubo versus anterior STEMI.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
    Observational
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Amelia E RuddAberdeen Cardiovascular and Diabetes Centre, University of Aberdeen and NHS Grampian, Aberdeen, United Kingdom.
Graham HorganBiomathematics & Statistics Scotland, Aberdeen, United Kingdom.
Hilal KhanAberdeen Cardiovascular and Diabetes Centre, University of Aberdeen and NHS Grampian, Aberdeen, United Kingdom.
David T GambleAberdeen Cardiovascular and Diabetes Centre, University of Aberdeen and NHS Grampian, Aberdeen, United Kingdom.
Jim McGowanUniversity Hospital Ayr, NHS Ayrshire and Arran, Ayr, United Kingdom.
Arvind SoodHairmyres Hospital, NHS Lanarkshire, East Kilbride, United Kingdom.
Ross McGeochHairmyres Hospital, NHS Lanarkshire, East Kilbride, United Kingdom.
John IrvingNHS Tayside, University of Dundee and Ninewells Hospital, Dundee, United Kingdom.
Jonathan WattNHS Highland, Raigmore Hospital, Inverness, United Kingdom.
Stephen J LeslieNHS Highland, Raigmore Hospital, Inverness, United Kingdom.
Mark PetrieInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom.
Chim LangNHS Tayside, University of Dundee and Ninewells Hospital, Dundee, United Kingdom.
Nicholas L MillsUsher Institute, University of Edinburgh, Edinburgh, United Kingdom; and the.
David E NewbyCentre for Cardiovascular Science and Usher Institute, University of Edinburgh and NHS Lothian, Edinburgh, United Kingdom.
Dana K DawsonAberdeen Cardiovascular and Diabetes Centre, University of Aberdeen and NHS Grampian, Aberdeen, United Kingdom.

Funding

British Heart Foundation CH/09/002/26360British Heart Foundation CH/F/21/90010British Heart Foundation FS/RTF/20/30009
6 · The paper itself

Abstract

Background: Takotsubo syndrome is an increasingly common cardiac emergency with no known evidence-based treatment. Objectives: The purpose of this study was to investigate cardiovascular mortality and medication use after takotsubo syndrome. Methods: In a case-control study, all patients with takotsubo syndrome in Scotland between 2010 and 2017 (n = 620) were age, sex, and geographically matched to individuals in the general population (1:4, n = 2,480) and contemporaneous patients with acute myocardial infarction (1:1, n = 620). Electronic health record data linkage of mortality outcomes and drug prescribing were analyzed using Cox proportional hazard regression models. Results: Of the 3,720 study participants (mean age, 66 years; 91% women), 153 (25%) patients with takotsubo syndrome died over the median of 5.5 years follow-up. This exceeded mortality rates in the general population (N = 374 [15%]; HR: 1.78 [95% CI: 1.48-2.15], Conclusions: In patients with takotsubo syndrome, cardiovascular mortality is the leading cause of death, and this is not associated with cardiovascular therapy use.

Indexed as

cardiovascularelectronic data linkagemedicationmortalitymyocardial infarctiontakotsubo

Identifiers

PMID38774915
PMCPMC7615966

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.