Evidence map›Paper›PMID 38774747›Full record

ArticleInternational journal of medical sciences2024

LncRNA RPL29P2 promotes peritoneal fibrosis and impairs peritoneal transport function via miR-1184 in peritoneal dialysis.

Huan Li, Yuting Zhang, Mingwen Che, Hanmin Wang, Sutong Li, Peng He, Shiren Sun, Guoshuang Xu, Chen Huang, Xiaowei Liu and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Huan LiDepartment of Nephrology, Xijing Hospital, the Fourth Military Medical University, Xi'an, Shaanxi, China.
Yuting ZhangDepartment of Nephrology, Xijing Hospital, the Fourth Military Medical University, Xi'an, Shaanxi, China.
Mingwen CheDepartment of Nephrology, Xijing Hospital, the Fourth Military Medical University, Xi'an, Shaanxi, China.
Hanmin WangDepartment of Nephrology, Xijing Hospital, the Fourth Military Medical University, Xi'an, Shaanxi, China.
Sutong LiDepartment of Nephrology, Xi'an Central Hospital, Xi'an, Shaanxi, China.
Peng HeDepartment of Nephrology, Xijing Hospital, the Fourth Military Medical University, Xi'an, Shaanxi, China.
Shiren SunDepartment of Nephrology, Xijing Hospital, the Fourth Military Medical University, Xi'an, Shaanxi, China.
Guoshuang XuDepartment of Nephrology, Xijing Hospital, the Fourth Military Medical University, Xi'an, Shaanxi, China.
Chen HuangDepartment of Nephrology, Xijing Hospital, the Fourth Military Medical University, Xi'an, Shaanxi, China.
Xiaowei LiuDepartment of Nephrology, Xijing Hospital, the Fourth Military Medical University, Xi'an, Shaanxi, China.
Ming BaiDepartment of Nephrology, Xijing Hospital, the Fourth Military Medical University, Xi'an, Shaanxi, China.
Meilan ZhouDepartment of Nephrology, Xijing Hospital, the Fourth Military Medical University, Xi'an, Shaanxi, China.
Binxiao SuDepartment of Anesthesiology and Perioperative Medicine, Department of Intensive Care Unit, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710032, China.
Peng ZhangDepartment of Nephrology, Xijing Hospital, the Fourth Military Medical University, Xi'an, Shaanxi, China.
Lijie HeDepartment of Nephrology, Xijing Hospital, the Fourth Military Medical University, Xi'an, Shaanxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peritoneal dialysis (PD), hemodialysis and kidney transplantation are the three therapies to treat uremia. However, PD is discontinued for peritoneal membrane fibrosis (PMF) and loss of peritoneal transport function (PTF) due to damage from high concentrations of glucose in PD fluids (PDFs). The mechanism behind PMF is unclear, and there are no available biomarkers for the evaluation of PMF and PTF. Using microarray screening, we found that a new long noncoding RNA (lncRNA), RPL29P2, was upregulated in the PM (peritoneal membrane) of long-term PD patients, and its expression level was correlated with PMF severity and the PTF loss.

Indexed as

Collagen Type I, alpha 1 ChainMicroRNAsPeritoneal DialysisPeritoneal FibrosisPeritoneumRNA, Long NoncodingAnimalsDisease Models, AnimalFemaleGlucoseHumansMiddle AgedRatsRats, Sprague-DawleyCOL1A1 protein, humanCollagen Type I, alpha 1 ChainGlucoseMicroRNAsMIRN1184 microRNA, humanRNA, Long NoncodingcollagenfibrosisLncRNA RPL29P2miR-1184peritoneal dialysisperitoneal transport function

Identifiers

PMID38774747
PMCPMC11103403

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.