Evidence map›Paper›PMID 38774639›Full record

ArticleComputational psychiatry (Cambridge, Mass.)2023

Electrophysiological Markers of Aberrant Cue-Specific Exploration in Hazardous Drinkers.

Ethan M Campbell, Garima Singh, Eric D Claus, Katie Witkiewitz, Vincent D Costa, Jeremy Hogeveen, James F Cavanagh

Abstract read
In one paragraph

Article in Computational psychiatry (Cambridge, Mass.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Spatiotemporal Decoding of Explore-Exploit Decisions in the Human Brain.bioRxiv : the preprint server for biology · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ethan M CampbellDepartment of Psychology & Psychology Clinical Neuroscience Center, University of New Mexico, US.ORCID https://orcid.org/0000-0002-9776-2313
Garima SinghDepartment of Psychology & Psychology Clinical Neuroscience Center, University of New Mexico, US.
Eric D ClausDepartment of Biobehavioral Health, Pennsylvania State University, US.ORCID https://orcid.org/0000-0002-1800-0813
Katie WitkiewitzDepartment of Psychology & Psychology Clinical Neuroscience Center, University of New Mexico, US.ORCID https://orcid.org/0000-0002-1086-3067
Vincent D CostaDivision of Neuroscience, Oregon National Primate Research Center, US.ORCID https://orcid.org/0000-0002-5412-8945
Jeremy HogeveenDepartment of Psychology & Psychology Clinical Neuroscience Center, University of New Mexico, US.ORCID https://orcid.org/0000-0001-9612-2085
James F CavanaghDepartment of Psychology & Psychology Clinical Neuroscience Center, University of New Mexico, US.

Funding

University of New Mexico (UNM) Center for Brain Recovery and RepairP20GM109089 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI SHUTTLEWORTH, CLAUDE W · 2015 to 2024
$22.7M
Neural Mechanisms of Behavior Change in a Community Sample of DrinkersR01AA023665 · NIAAA · THE MIND RESEARCH NETWORK · PI CLAUS, ERIC D, WITKIEWITZ, KATIE A · 2015 to 2019
$3.6M
A Novel Bench-to-Bedside Translational Model of AnhedoniaR01MH119382 · NIMH · UNIVERSITY OF NEW MEXICO · PI CAVANAGH, JAMES F · 2019 to 2023
$1.8M
NIAAA NIH HHS R01 AA023665NIGMS NIH HHS P20 GM109089NIMH NIH HHS R01 MH119382
6 · The paper itself

Abstract

Background: Hazardous drinking is associated with maladaptive alcohol-related decision-making. Existing studies have often focused on how participants learn to exploit familiar cues based on prior reinforcement, but little is known about the mechanisms that drive hazardous drinkers to explore novel alcohol cues when their value is not known. Methods: We investigated exploration of novel alcohol and non-alcohol cues in hazardous drinkers (N = 27) and control participants (N = 26) during electroencephalography (EEG). A normative computational model with two free parameters was fit to estimate participants' weighting of the future value of exploration and immediate value of exploitation. Results: Hazardous drinkers demonstrated increased exploration of novel alcohol cues, and conversely, increased probability of exploiting familiar alternatives instead of exploring novel non-alcohol cues. The motivation to explore novel alcohol stimuli in hazardous drinkers was driven by an elevated relative future valuation of uncertain alcohol cues. P3a predicted more exploratory decision policies driven by an enhanced relative future valuation of novel alcohol cues. P3b did not predict choice behavior, but computational parameter estimates suggested that hazardous drinkers with enhanced P3b to alcohol cues were likely to learn to exploit their immediate expected value. Conclusions: Hazardous drinkers did not display atypical choice behavior, different P3a/P3b amplitudes, or computational estimates to novel

Indexed as

addictionalcoholexplore-exploitP3aPOMDP

Identifiers

PMID38774639
PMCPMC11104413

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.