Evidence map›Paper›PMID 38774588›Full record

ArticleFrontiers in allergy2024

Oral immunotherapy with enteric-coated capsules for allergic rhinitis caused by house dust mites.

Han-Zhong Zhang, Wei Xie, Wen-Cheng Zhou, Jian Chen, Ying Wang, Yuan-Yuan Zhu, Ting-Huan Wen, Lei Cheng

Abstract read
In one paragraph

Article in Frontiers in allergy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Han-Zhong Zhang *Department of Otorhinolaryngology, Wuxi Hospital of Traditional Chinese Medicine, Wuxi, China.
Wei Xie *Department of Otorhinolaryngology, Wuxi Hospital of Traditional Chinese Medicine, Wuxi, China.
Wen-Cheng Zhou *Department of Otorhinolaryngology & Clinical Allergy Center, The First Affiliated Hospital, Nanjing Medical University, Nanjing, China.
Jian ChenDepartment of Otorhinolaryngology, Wuxi Hospital of Traditional Chinese Medicine, Wuxi, China.
Ying WangDepartment of Otorhinolaryngology, Wuxi Hospital of Traditional Chinese Medicine, Wuxi, China.
Yuan-Yuan ZhuDepartment of Otorhinolaryngology, Wuxi Hospital of Traditional Chinese Medicine, Wuxi, China.
Ting-Huan WenMites Laboratory, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Lei ChengDepartment of Otorhinolaryngology & Clinical Allergy Center, The First Affiliated Hospital, Nanjing Medical University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Oral immunotherapy (OIT) is a promising allergen-specific approach in the management of food allergy; however, studies on OIT for allergic rhinitis (AR) have rarely been reported. The purpose of this study is to evaluate the efficacy and safety of OIT using enteric-coated capsules for AR induced by house dust mites. Methods: A total of 49 patients with AR were enrolled, including 25 who received subcutaneous immunotherapy (SCIT) and 24 who received OIT. The clinical efficacy and safety in both groups were evaluated. Results: After 1 year of treatment, both SCIT and OIT demonstrated significant therapeutic effects. OIT was found to be more effective than SCIT in reducing the total AR symptom score and improving the results of nasal provocation tests. Local and systemic adverse reactions were observed in the SCIT group, while none were reported in the OIT group. Conclusion: OIT is an effective and safe treatment for mite-induced AR.

Indexed as

allergic rhinitisenteric-coated capsulesmitesoral immunotherapysubcutaneous immunotherapy

Identifiers

PMID38774588
PMCPMC11106396

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.