Evidence map›Paper›PMID 38774567›Full record

ArticleEcancermedicalscience2024

Is the incidence rate of colorectal cancer increasing in Mozambique?

Carlos Selemane, Josefo Ferro, Cesaltina Lorenzoni, Carla Carrilho, Mamudo Rafik Ismail, Max Parkin, Lúcio Lara Santos

Abstract read
In one paragraph

Article in Ecancermedicalscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carlos SelemaneDepartment of Surgery, Maputo Central Hospital, Av Agostinho Neto n° 164, Maputo 1164, Mozambique.
Josefo FerroDepartment of Pathology, Beira Central Hospital, Av Mártires da Revolução nº 727, Beira, Mozambique.
Cesaltina LorenzoniDepartment of Pathology, Faculty of Medicine, Eduardo Mondlane University, and Maputo Central Hospital, Av Agostinho Neto n° 164, Maputo 1164, Mozambique.
Carla CarrilhoDepartment of Pathology, Faculty of Medicine, Eduardo Mondlane University, and Maputo Central Hospital, Av Agostinho Neto n° 164, Maputo 1164, Mozambique.
Mamudo Rafik IsmailDepartment of Pathology, Faculty of Medicine, Eduardo Mondlane University, and Maputo Central Hospital, Av Agostinho Neto n° 164, Maputo 1164, Mozambique.
Max ParkinAfrican Cancer Registry Network, Prama House, 267 Banbury Road, Oxford OX2 7HT, UK.
Lúcio Lara SantosExperimental Pathology and Therapeutics Research Group and Surgical Oncology Department, Portuguese Institute of Oncology, Dr António Bernardino de Almeida Street, Porto 4200-072, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Colorectal cancer (CRC) is a significant global health concern, ranking as the third most common cancer and the second leading cause of cancer-related deaths. However, in Africa, CRC is the fifth most common invasive malignancy. Limited data hinder our understanding of the evolving burden of CRC in sub-Saharan Africa. This study explores CRC trends in Mozambique, utilising data from population-based oncological registries. Methods: CRC data were gathered from Beira and Maputo population-based cancer registries, along with supplementary information from pathology-based and hospital-based registries. Comparative analyses were performed across different time periods, focusing on trends and epidemiological characteristics. Results: Incidence rates of CRC in Maputo and Beira were relatively low historically. However, data from recent years showed an increase, especially in age groups above 50. Analyses from pathology-based and hospital-based registries affirmed the rising trend. The age-standardised incidence rate in Maputo (2015-2017) was 3.17 for males and 2.55 for females. Beira exhibited increasing rates between 2009 and 2020, particularly in individuals aged 50 and above. Conclusion: The study reveals an emerging burden of CRC in Mozambique, challenging the perception of low incidence. The rising trend underscores the necessity for tailored interventions, emphasizing early diagnosis, preventive strategies, and investments in healthcare infrastructure to address the increasing CRC burden in the region.

Indexed as

colorectal cancerdeveloping countriesincidence rateMozambique

Identifiers

PMID38774567
PMCPMC11108046

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.