Evidence map›Paper›PMID 38774483›Full record

ReviewDrug design, development and therapy2024

Effects of Natural Products through Inhibiting Endoplasmic Reticulum Stress on Attenuation of Idiopathic Pulmonary Fibrosis.

JiuLing Deng, Jing Liu, WanSheng Chen, Qing Liang, YuQiong He, GuangChun Sun

Abstract readReview
In one paragraph

Review in Drug design, development and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

JiuLing Deng *Department of Pharmacy, Shanghai Fifth People's Hospital, Fudan University, Shanghai, 200240, People's Republic of China.ORCID 0009-0009-1932-894X
Jing Liu *Department of Pharmacy, Shanghai Fifth People's Hospital, Fudan University, Shanghai, 200240, People's Republic of China.
WanSheng Chen *Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People's Republic of China.
Qing LiangDepartment of Pharmacy, Shanghai Fifth People's Hospital, Fudan University, Shanghai, 200240, People's Republic of China.
YuQiong HeInstitute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People's Republic of China.
GuangChun SunDepartment of Pharmacy, Shanghai Fifth People's Hospital, Fudan University, Shanghai, 200240, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With ever-increasing intensive studies of idiopathic pulmonary fibrosis (IPF), significant progresses have been made. Endoplasmic reticulum stress (ERS)/unfolded protein reaction (UPR) is associated with the development and progression of IPF, and targeting ERS/UPR may be beneficial in the treatment of IPF. Natural product is a tremendous source of new drug discovery, and accumulating studies have reported that many natural products show potential therapeutic effects for IPF via modulating one or more branches of the ERS signaling pathway. Therefore, this review focuses on critical roles of ERS in IPF development, and summarizes herbal preparations and bioactive compounds which protect against IPF through regulating ERS.

Indexed as

Biological ProductsEndoplasmic Reticulum StressIdiopathic Pulmonary FibrosisAnimalsHumansSignal TransductionUnfolded Protein ResponseBiological Productsendoplasmic reticulum stressidiopathic pulmonary fibrosismechanismsnatural products

Identifiers

PMID38774483
PMCPMC11108075

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.