Evidence map›Paper›PMID 38774352›Full record

ArticleBiophysics reports2024

Morphological determination of localization and function of Golgi proteins.

Yusheng Xing, Yannan Jian, Xiaodan Zhao, Yue Zhang, Zhenqian Zhang, Xing Zhang, Xiaoyan Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biophysics reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yusheng XingCollege of Biomedicine and Health, College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Yannan JianCollege of Biomedicine and Health, College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Xiaodan ZhaoCollege of Biomedicine and Health, College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Yue ZhangCollege of Biomedicine and Health, College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Zhenqian ZhangCollege of Biomedicine and Health, College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Xing ZhangCollege of Biomedicine and Health, College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Xiaoyan ZhangCollege of Biomedicine and Health, College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In animal cells, the Golgi apparatus serves as the central hub of the endomembrane secretory pathway. It is responsible for the processing, modification, and sorting of proteins and lipids. The unique stacking and ribbon-like architecture of the Golgi apparatus forms the foundation for its precise functionality. Under cellular stress or pathological conditions, the structure of the Golgi and its important glycosylation modification function may change. It is crucial to employ suitable methodologies to study the structure and function of the Golgi apparatus, particularly when assessing the involvement of a target protein in Golgi regulation. This article provides a comprehensive overview of the diverse microscopy techniques used to determine the specific location of the target protein within the Golgi apparatus. Additionally, it outlines methods for assessing changes in the Golgi structure and its glycosylation modification function following the knockout of the target gene.

Indexed as

Electron microscopyGlycosylationGolgi apparatusGolgi fragmentationImmunofluorescenceLectin stainingSuper-resolution microscopy

Identifiers

PMID38774352
PMCPMC11103716

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.