Evidence map›Paper›PMID 38774148›Full record

ArticleARKIVOC : free online journal of organic chemistry2021

An efficient debromination technique using PMHS with a number of ligands containing different functional groups.

Md Yeunus Mian, Prithu Mondal, Dishary Sharmin, Kamal P Pandey, Farjana Rashid, Sepideh Rezvanian, Lalit K Golani, V V N Phani Babu Tiruveedhula, Vilashini Rajaratnam, Shama P Mirza and 3 more

Abstract read
PubMed Full text at PMC
In one paragraph

Article in ARKIVOC : free online journal of organic chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Md Yeunus MianDepartment of Chemistry and Biochemistry, Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI-53211.
Prithu MondalDepartment of Chemistry and Biochemistry, Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI-53211.
Dishary SharminDepartment of Chemistry and Biochemistry, Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI-53211.
Kamal P PandeyDepartment of Chemistry and Biochemistry, Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI-53211.
Farjana RashidDepartment of Chemistry and Biochemistry, Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI-53211.
Sepideh RezvanianDepartment of Chemistry and Biochemistry, Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI-53211.
Lalit K GolaniDepartment of Chemistry and Biochemistry, Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI-53211.
V V N Phani Babu TiruveedhulaDepartment of Chemistry and Biochemistry, Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI-53211.
Vilashini RajaratnamDepartment of Chemistry and Biochemistry, Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI-53211.
Shama P MirzaDepartment of Chemistry and Biochemistry, Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI-53211.
John D ChanDepartment of Chemistry, University of Wisconsin-Oshkosh, Oshkosh, WI-54901.
Jeffrey M WitkinDepartment of Chemistry and Biochemistry, Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI-53211.
James M CookDepartment of Chemistry and Biochemistry, Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI-53211.

Funding

Tolerance and Physical Dependence after Chronic Benzodiazepine TreatmentR01DA043204 · NIDA · UNIVERSITY OF MISSISSIPPI MED CTR · PI JAMES K ROWLETT · 2017 to 2026
$4.3M
Synthesis of Alpha2/Alpha3 GABA Agonists to Treat Neuropathic PainR01NS076517 · NINDS · UNIVERSITY OF WISCONSIN MILWAUKEE · PI COOK, JAMES M · 2012 to 2015
$1.3M
Development of non-sedative, parasite-selective benzodiazepines to treat the neglected tropical disease schistosomiasisR21AI146540 · NIAID · UNIVERSITY OF WISCONSIN OSHKOSH · PI CHAN, JOHN D · 2020 to 2021
$405k
NIAID NIH HHS R21 AI146540NIDA NIH HHS R01 DA043204NINDS NIH HHS R01 NS076517
6 · The paper itself

Abstract

Herein is described the strategy to debrominate different aryl bromides selectively, using polymethylhydrosiloxane (PMHS) which tolerates a variety of functional groups. Key elements of this approach include the use of catalytic Pd(OAc)

Indexed as

benzodiazepinesdebrominationpalladium acetatepolymethylhydrosiloxane

Identifiers

PMID38774148
PMCPMC11107800

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.