Evidence map›Paper›PMID 38773978›Full record

ArticleTheranostics2024

Small extracellular vesicles (sEVs)-based gene delivery platform for cell-specific CRISPR/Cas9 genome editing.

Sunil Dubey, Zhe Chen, Yuxiao Jarvan Jiang, Austin Talis, Andrei Molotkov, Alessandra Ali, Akiva Mintz, Fatemeh Momen-Heravi

Abstract read
In one paragraph

Article in Theranostics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Overview of Delivery Methods for Gene Editing.Methods in molecular biology (Clifton, N.J.) · 2027
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  5. Article
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  10. International journal of biological sciences · 2026
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  17. Treating genetic blood disorders in the era of CRISPR-mediated genome editing.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sunil DubeyCancer Biology and Immunology Laboratory, Columbia University Irving Medical Center, NY, New York, USA.
Zhe ChenCancer Biology and Immunology Laboratory, Columbia University Irving Medical Center, NY, New York, USA.
Yuxiao Jarvan JiangCancer Biology and Immunology Laboratory, Columbia University Irving Medical Center, NY, New York, USA.
Austin TalisCancer Biology and Immunology Laboratory, Columbia University Irving Medical Center, NY, New York, USA.
Andrei MolotkovDepartment of Radiology, Columbia University Irving Medical Center, New York, NY, USA.
Alessandra AliDepartment of Radiology, Columbia University Irving Medical Center, New York, NY, USA.
Akiva MintzDepartment of Radiology, Columbia University Irving Medical Center, New York, NY, USA.
Fatemeh Momen-HeraviCancer Biology and Immunology Laboratory, Columbia University Irving Medical Center, NY, New York, USA.

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ANIRBAN MAITRA · 1985 to 2026
$83.1M
Immune and transcriptomic biomarkers of progressive oral premalignant lesionsU01DE033351 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Fatemeh Momen Heravi · 2023 to 2026
$3.1M
Role of Long Non-Coding RNAs in Exosome BiogenesisR35GM151259 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Fatemeh Momen Heravi · 2023 to 2026
$1.6M
NCI NIH HHS P30 CA016087NIDCR NIH HHS L30 DE029070NIDCR NIH HHS U01 DE033351NIGMS NIH HHS R35 GM151259
6 · The paper itself

Abstract

Small extracellular vesicles (sEVs) are naturally occurring vesicles that have the potential to be manipulated to become promising drug delivery vehicles for on-demand

Indexed as

CRISPR-Cas SystemsExtracellular VesiclesGene EditingGene Transfer TechniquesAnimalsHumansMiceRibonucleoproteinsRNA, Guide, CRISPR-Cas SystemsRNA, Small InterferingRibonucleoproteinsRNA, Guide, CRISPR-Cas SystemsRNA, Small InterferingCasCRISPRDeliveryGenome EditingsEVs

Identifiers

PMID38773978
PMCPMC11103490

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.