Evidence map›Paper›PMID 38773719›Full record

ArticleJournal of applied clinical medical physics2024

Automated segmentation of liver and hepatic vessels on portal venous phase computed tomography images using a deep learning algorithm.

Shengwei Li, Xiao-Guang Li, Fanyu Zhou, Yumeng Zhang, Zhixin Bie, Lin Cheng, Jinzhao Peng, Bin Li

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Article in Journal of applied clinical medical physics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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3 · Its place in the literature

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4 citing papers in PubMed.

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5 · Who and what money

Authors and funding

8 authors.

Shengwei LiMinimally Invasive Tumor Therapy Center, Beijing Hospital, Peking Union Medical College, Beijing, China.
Xiao-Guang LiMinimally Invasive Tumor Therapy Center, Beijing Hospital, Peking Union Medical College, Beijing, China.ORCID https://orcid.org/0000-0002-3345-1313
Fanyu ZhouMinimally Invasive Tumor Therapy Center, Beijing Hospital, Peking Union Medical College, Beijing, China.
Yumeng ZhangMinimally Invasive Tumor Therapy Center, Beijing Hospital, Peking Union Medical College, Beijing, China.
Zhixin BieMinimally Invasive Tumor Therapy Center, Beijing Hospital, Peking Union Medical College, Beijing, China.
Lin ChengMinimally Invasive Tumor Therapy Center, Beijing Hospital, Peking Union Medical College, Beijing, China.
Jinzhao PengMinimally Invasive Tumor Therapy Center, Beijing Hospital, Peking Union Medical College, Beijing, China.
Bin LiMinimally Invasive Tumor Therapy Center, Beijing Hospital, Peking Union Medical College, Beijing, China.

Funding

National High Level Hospital Clinical Research BJ-2022-106
6 · The paper itself

Abstract

backgroundCT-image segmentation for liver and hepatic vessels can facilitate liver surgical planning. However, time-consuming process and inter-observer variations of manual segmentation have limited wider application in clinical practice. PURPOSE: Our study aimed to propose an automated deep learning (DL) segmentation algorithm for liver and hepatic vessels on portal venous phase CT images.

methodsThis retrospective study was performed to develop a coarse-to-fine DL-based algorithm that was trained, validated, and tested using private 413, 52, and 50 portal venous phase CT images, respectively. Additionally, the performance of the DL algorithm was extensively evaluated and compared with manual segmentation using an independent clinical dataset of preoperative contrast-enhanced CT images from 44 patients with hepatic focal lesions. The accuracy of DL-based segmentation was quantitatively evaluated using the Dice Similarity Coefficient (DSC) and complementary metrics [Normalized Surface Dice (NSD) and Hausdorff distance_95 (HD95) for liver segmentation, Recall and Precision for hepatic vessel segmentation]. The processing time for DL and manual segmentation was also compared.

resultsOur DL algorithm achieved accurate liver segmentation with DSC of 0.98, NSD of 0.92, and HD95 of 1.52 mm. DL-segmentation of hepatic veins, portal veins, and inferior vena cava attained DSC of 0.86, 0.89, and 0.94, respectively. Compared with the manual approach, the DL algorithm significantly outperformed with better segmentation results for both liver and hepatic vessels, with higher accuracy of liver and hepatic vessel segmentation (all p < 0.001) in independent 44 clinical data. In addition, the DL method significantly reduced the manual processing time of clinical postprocessing (p < 0.001).

conclusionsThe proposed DL algorithm potentially enabled accurate and rapid segmentation for liver and hepatic vessels using portal venous phase contrast CT images.

Indexed as

AlgorithmsDeep LearningImage Processing, Computer-AssistedLiver NeoplasmsPortal VeinTomography, X-Ray ComputedAdultAgedFemaleHepatic VeinsHumansLiverMaleMiddle AgedPrognosisRetrospective Studiescomputed tomographydeep learningliversegmentation

Identifiers

PMID38773719
PMCPMC11302809

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.