Evidence map›Paper›PMID 38773614›Full record

ArticleJournal of nanobiotechnology2024

Multiarmed DNA jumper and metal-organic frameworks-functionalized paper-based bioplatform for small extracellular vesicle-derived miRNAs assay.

Xiaopei Qiu, Huisi Yang, Man Shen, Hanqing Xu, Yingran Wang, Shuai Liu, Qian Liu, Minghui Sun, Zishan Ding, Ligai Zhang and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nanobiotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Xiaopei Qiu *Department of Clinical Laboratory Medicine, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, P. R. China.
Huisi Yang *Key Laboratory for Biorheological Science and Technology of Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, 400044, PR China.
Man ShenDepartment of Clinical Laboratory Medicine, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, P. R. China.
Hanqing XuDepartment of Clinical Laboratory Medicine, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, P. R. China.
Yingran WangDepartment of Clinical Laboratory Medicine, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, P. R. China.
Shuai LiuDepartment of Clinical Laboratory Medicine, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, P. R. China.
Qian LiuDepartment of Clinical Laboratory Medicine, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, P. R. China.
Minghui SunDepartment of Clinical Laboratory Medicine, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, P. R. China.
Zishan DingDepartment of Clinical Laboratory Medicine, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, P. R. China.
Ligai ZhangDepartment of Clinical Laboratory Medicine, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, P. R. China.
Jun WangDepartment of Clinical Laboratory Medicine, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, P. R. China.
Taotao LiangChongqing Sports Medicine Center, Department of Orthopedic Surgery, Department of Clinical Laboratory Medicine, Southwest Hospital, the Third Military Medical University, Chongqing, 400038, P.R. China.
Dan LuoDepartment of Biological and Environmental Engineering, Cornell University, Ithaca, NY, 14853-5701, USA.
Mingxuan GaoDepartment of Clinical Laboratory Medicine, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, P. R. China. mingxuan_gao@163.com.
Ming ChenDepartment of Clinical Laboratory Medicine, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, P. R. China. chming1971@126.com.
Jing BaoDepartment of Clinical Laboratory Medicine, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, P. R. China. baojing_1991@163.com.

Funding

National Natural Science Foundation of China 32371473National Natural Science Foundation of China 82002251National Natural Science Foundation of China 82030066National Natural Science Foundation of China 82102635Natural Science Foundation Project of Chongqing, Chongqing Science and Technology Commission CSTB2022NSCQ-MSX0151
6 · The paper itself

Abstract

Small extracellular vesicle-derived microRNAs (sEV-miRNAs) have emerged as promising noninvasive biomarkers for early cancer diagnosis. Herein, we developed a molecular probe based on three-dimensional (3D) multiarmed DNA tetrahedral jumpers (mDNA-Js)-assisted DNAzyme activated by Na

Indexed as

Biosensing TechniquesExtracellular VesiclesLimit of DetectionMetal-Organic FrameworksMicroRNAsPaperDNADNA, CatalyticElectrochemical TechniquesElectrodesGoldGraphiteHumansMetal NanoparticlesNucleic Acid HybridizationZirconiumDNADNA, CatalyticGoldgraphene oxideGraphiteMetal-Organic FrameworksMicroRNAsMIRN21 microRNA, humanZirconiumMetal–organic frameworksMultiarmed DNA tetrahedral jumpersPoint-of-care diagnosisSmall extracellular vesicle–derived microRNAsWireless Biosensor

Identifiers

PMID38773614
PMCPMC11110235

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.