Evidence map›Paper›PMID 38773505›Full record

ArticleImplementation science communications2024

Feasibility, acceptability and preliminary effect of a community-led HIV self-testing model among adolescent girls and young women in Rural Northern Uganda: a quasi-experimental study protocol.

Ronald Olum, Elvin H Geng, Freddy E Kitutu, Philippa M Musoke

Abstract read
In one paragraph

Article in Implementation science communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ronald OlumMakerere University School of Public Health, Kampala, Uganda. olum.ronald@gmail.com.
Elvin H GengDivision of Infectious Diseases, Department of Medicine, Washington University in St Louis, MO, St Louis, USA.
Freddy E KitutuDepartment of Pharmacy, School of Health Sciences, Makerere University, Kampala, Uganda.
Philippa M MusokeDepartment of Pediatrics and Child Health, School of Medicine, Makerere University College of Health Sciences, Kampala, Uganda.

Funding

Addressing the Research Capacity Gap in Global Child and Adolescent Health Disparities Utilizing Implementation and Data Sciences among Vulnerable Populations in Resource-limited Settings (ACHIEVE)D43TW012275 · FIC · WASHINGTON UNIVERSITY · PI Theresa Stichick Betancourt, Mary McKernan McKay · 2022 to 2026
$7.2M
FIC NIH HHS D43 TW012275Gilead Research Scholars Gilead Research Scholars
6 · The paper itself

Abstract

backgroundAdolescent girls and young women (AGYW) in sub-Saharan Africa face a disproportionately higher HIV/AIDS burden despite the global decline in incidence. Existing interventions often fail to adequately address their unique social, economic, and cultural challenges, limiting access to essential HIV/AIDS services, including HIV testing. Emerging evidence indicates that HIV self-testing, a user-friendly and confidential method, enhances HIV diagnosis and linkage to care by targeting these barriers. This study aims to assess the feasibility, acceptability, and preliminary impact of a peer-delivered, community-health worker (CHW)-facilitated HIV self-testing intervention for AGYW in Northern Uganda.

methodsThis mixed-methods quasi-experimental implementation science study will employ a three-fold approach. Firstly, we will conduct baseline formative qualitative research with 50 AGYW, 50 parents/partners to AGYW, 30 CHWs, 15 community leaders, and the district health office to inform the design of a peer-delivered CHW-facilitated HIV self-testing intervention tailored to AGYW's needs in Northern Uganda. Secondly, we will implement a mixed-methods pilot study to assess the intervention's feasibility and acceptability, involving 415 AGYW, 30 AGYW peer leaders, and 10 CHWs in selected parishes and villages in Omoro district, Northern Uganda. Lastly, we will evaluate the implementation outcomes and preliminary impact of the intervention on HIV self-testing rates and linkage to care by collecting and analyzing quantitative data pre- and post-intervention, laying the groundwork for a future robust randomized controlled trial. DISCUSSION: Our intervention combines CHWs and peer-led strategies to address the unique challenges of AGYW in Northern Uganda, leveraging community resilience and peer influence. Successful completion of this project will provide a scalable model to be evaluated in a randomized trial and replicated in similar contexts. TRIAL REGISTRATION NUMBER: PACTR202404851907736. Registered with the Pan-African Clinical Trials Registry on April 22, 2024.

Indexed as

Adolescent girlsHIV/AIDSSelf-testingSub-saharan AfricaYoung women

Identifiers

PMID38773505
PMCPMC11110295

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.