Evidence map›Paper›PMID 38773438›Full record

ArticleBMC oral health2024

The 8th AJCC classification is inferior to a new neck stage based on intraparotid lymph node in parotid gland cancer.

Xiaoxue Han, Changyu Yang, Xuexin Tan, Yuexiao Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaoxue HanDepartment of Oral and Maxillofacial Surgery, School of Stomatology, China Medical University, No.117 Nanjing North Street, Heping District, Shenyang, 110002, Liaoning, P.R. China.
Changyu YangDepartment of Stomatology, The Fourth Affiliated Hospital of China Medical University, Shenyang, P.R. China.
Xuexin TanDepartment of Oral and Maxillofacial Surgery, School of Stomatology, China Medical University, No.117 Nanjing North Street, Heping District, Shenyang, 110002, Liaoning, P.R. China.
Yuexiao LiDepartment of Oral and Maxillofacial Surgery, School of Stomatology, China Medical University, No.117 Nanjing North Street, Heping District, Shenyang, 110002, Liaoning, P.R. China. liyuexiaocmu@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLymph node (LN) status is an important prognostic factor for parotid gland cancer (PGC). This study aimed to analyze the impact of extranodal extension (ENE) of intraparotid LN and LN metastasis burden on survival in PGC.

methodsPatients with surgically treated PGC and at least one metastatic cervical LN were retrospectively enrolled. Primary outcome variables were distant metastasis-free survival (DMFS), disease-specific survival (DSS), and overall survival (OS). The impact of ENE and LN metastasis burden was assessed using the Cox model.

resultsA total of 292 patients were included. ENE in cervical or intraparotid LN was not associated with DMFS, DSS, or OS. Intraparotid LN metastasis had a significant impact on prognosis, and the presence of only one metastatic intraparotid LN offered an approximately 1.5-fold risk of distant metastasis. Prognostic models based on the number of positive LNs (1 vs. 2-3 vs. 4+) were superior to the AJCC N stage in terms of DMFS, DSS, and OS.

conclusionsENE of cervical or intraparotid LN has a limited effect on the prognosis of PGC, and the number of positive LNs is better than the AJCC N stage in LN status evaluation.

Indexed as

Lymphatic MetastasisLymph NodesNeoplasm StagingParotid NeoplasmsAdultAgedAged, 80 and overDisease-Free SurvivalExtranodal ExtensionFemaleHumansMaleMiddle AgedNeckPrognosisRetrospective StudiesAJCCExtranodal extensionIntraparotid lymph nodeLymph node burdenParotid cancer

Identifiers

PMID38773438
PMCPMC11110248

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.