ArticleNature communications2024
Modulate stress distribution with bio-inspired irregular architected materials towards optimal tissue support.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Bioinspired Mechanical Structures for Load Bearing and Energy Absorption: Cross-Scale Design and Fabrication Strategies.Biomimetics (Basel, Switzerland) · 2026Review
- Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling.Advanced healthcare materials · 2026Review
- Lattice Genome Framework for Regionally Tailored Component-Level Multi-Objective Design in Additive Manufacturing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Hydrogel-Based Vat Photopolymerization of Ceramics and Metals with Low Shrinkages via Repeated Infusion Precipitation.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Giga-Voxel Multiscale Composite Architecture Mirrored Through a Data-to-Model Closed-Loop Digital Twin.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Data-driven inverse design of multifunctional bicontinuous multiscale structures.Nature communications · 2026Article
- Multifaceted mechanical responsive metamaterials: Mechanisms, fabrications, and applications.Innovation (Cambridge (Mass.)) · 2026Review
- Self-supervised AI for decoding and designing disordered metamaterials.Science advances · 2026Article
- Diffusion Model-Based Design of Bionic Bone Scaffolds with Tunable Microstructures.Annals of biomedical engineering · 2025Article
- Bio-inspired material-structure-function integrated additive manufacturing of Al-based metamaterials with surpassing energy absorption.Science advances · 2025Article
- Static mechanical cloaking and camouflage from disorder.Nature communications · 2025Article
- Rational assembly of 3D network materials and electronics through tensile buckling.Science advances · 2025Article
- Multi-Physical Lattice Metamaterials Enabled by Additive Manufacturing: Design Principles, Interaction Mechanisms, and Multifunctional Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Natural materials typically exhibit irregular and non-periodic architectures, endowing them with compelling functionalities such as body protection, camouflage, and mechanical stress modulation. Among these functionalities, mechanical stress modulation is crucial for homeostasis regulation and tissue remodeling. Here, we uncover the relationship between stress modulation functionality and the irregularity of bio-inspired architected materials by a generative computational framework. This framework optimizes the spatial distribution of a limited set of basic building blocks and uses these blocks to assemble irregular materials with heterogeneous, disordered microstructures. Despite being irregular and non-periodic, the assembled materials display spatially varying properties that precisely modulate stress distribution towards target values in various control regions and load cases, echoing the robust stress modulation capability of natural materials. The performance of the generated irregular architected materials is experimentally validated with 3D printed physical samples - a good agreement with target stress distribution is observed. Owing to its capability to redirect loads while keeping a proper amount of stress to stimulate bone repair, we demonstrate the potential application of the stress-programmable architected materials as support in orthopedic femur restoration.
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Registered trials
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