Evidence map›Paper›PMID 38773035›Full record

Trial reportBiological trace element research2025

Bedsore Healing Using Selenium-Enriched Lactobacillus brevis LSe: A Randomized, Double-Blind, Controlled Clinical Trial.

Farshid Ataollahi, Bagher Amirheidari, Mehdi Ahmadinejad, Zahra Khoshnam, Mojtaba Shakibaie, Hamid Forootanfar, Maryam Nooshadokht, Mohammad Shabani, Maryam Ramezani Nejad, Adeleh Khodabakhshi and 1 more

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Biological trace element research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Iranian journal of microbiology · 2026
    Article
  2. The dual role of the microbiome in chronic wound management.Cell communication and signaling : CCS · 2026
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Farshid AtaollahiExtremophile and Productive Microorganisms Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Bagher AmirheidariExtremophile and Productive Microorganisms Research Center, Kerman University of Medical Sciences, Kerman, Iran. b_amirheidari@kmu.ac.ir.
Mehdi AhmadinejadDepartment of Anesthesiology, Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Zahra KhoshnamDepartment of Anesthesiology, Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Mojtaba ShakibaiePharmaceutical Sciences and Cosmetic Products Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Hamid ForootanfarPharmaceutical Sciences and Cosmetic Products Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Maryam NooshadokhtExtremophile and Productive Microorganisms Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Mohammad ShabaniKerman Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Science, Kerman, Iran.
Maryam Ramezani NejadExtremophile and Productive Microorganisms Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Adeleh KhodabakhshiDepartment of Nutrition, Faculty of Public Health, Kerman University of Medical Sciences, Kerman, Iran.
Zohreh AmirheidariExtremophile and Productive Microorganisms Research Center, Kerman University of Medical Sciences, Kerman, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bedsores impose an important challenge to the healthcare system. Se-baring probiotics are considered effective agents in wound healing and inflammation reduction via several pathways. The present study focused on the administration of a Se-enriched probiotic, originally obtained from a traditional dairy product for bedsore healing. Daily doses of the probiotic were administered to 20 ICU patients for 14 days and the wound healing criteria were compared with those of the same group of ICU patients as control, both groups suffering from stages I and II bedsore (a randomized, double-blind, controlled clinical trial). The administered Se-enriched probiotic decreased the bedsore healing period significantly (on average by 2.4 days, P-value: 0.039), as well as bedsore size (on average by 7 mm

Indexed as

Levilactobacillus brevisPressure UlcerProbioticsSeleniumWound HealingAdultAgedDouble-Blind MethodFemaleHumansMaleMiddle AgedSeleniumBedsoreHealingLactobacillusPressure ulcerProbioticsSeleniumSelenium enriched

Identifiers

PMID38773035

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.