Evidence map›Paper›PMID 38773013›Full record

ArticleMetabolomics : Official journal of the Metabolomic Society2024

Workshop report - interdisciplinary metabolomic epidemiology: the pathway to clinical translation.

Krista A Zanetti, Lining Guo, Deeba Husain, Rachel S Kelly, Jessica Lasky-Su, David Broadhurst, Craig E Wheelock

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolomics : Official journal of the Metabolomic Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Krista A ZanettiOffice of Nutrition Research, Division of Program Coordination, Planning, and Strategic Initiatives, Office of the Director, National Institutes of Health, Bethesda, MD, USA. zanettik@mail.nih.gov.
Lining Guo, Cary, NC, USA.
Deeba HusainMass Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
Rachel S KellyChanning Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Jessica Lasky-SuChanning Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
David BroadhurstSchool of Science, Edith Cowan University, Joondalup, Perth, Western Australia.
Craig E WheelockUnit of Integrative Metabolomics, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

Funding

Metabolomics a Novel Tool for Investigating the Pathogenesis of Age-related Macular DegenerationR01EY030088 · NEI · MASSACHUSETTS EYE AND EAR INFIRMARY · PI Deeba Husain · 2020 to 2026
$3.5M
Multi-Omic Endotyping of AsthmaK01HL146980 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI KELLY, RACHEL SABINE · 2019 to 2023
$891k
NEI NIH HHS R01 EY030088NHLBI NIH HHS K01 HL146980
6 · The paper itself

Abstract

Metabolomic epidemiology studies are complex and require a broad array of domain expertise. Although many metabolite-phenotype associations have been identified; to date, few findings have been translated to the clinic. Bridging this gap requires understanding of both the underlying biology of these associations and their potential clinical implications, necessitating an interdisciplinary team approach. To address this need in metabolomic epidemiology, a workshop was held at Metabolomics 2023 in Niagara Falls, Ontario, Canada that highlighted the domain expertise needed to effectively conduct these studies -- biochemistry, clinical science, epidemiology, and assay development for biomarker validation -- and emphasized the role of interdisciplinary teams to move findings towards clinical translation.

Indexed as

MetabolomicsTranslational Research, BiomedicalBiomarkersHumansOntarioBiomarkersClinical translationInterdisciplinary researchMetabolomic epidemiology

Identifiers

PMID38773013
PMCPMC11108898

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.