ReviewJournal of separation science2024
Update on chiral recognition mechanisms in separation science.
Review in Journal of separation science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Enantioselective HPLC of Liquid Crystals Bearing a Small and Flexible 2-Methylbutyl Chiral Center.Journal of separation science · 2026Article
- Cyclodextrins as Chiral Selectors in Capillary Electrophoresis-Recent Developments in Understanding Analyte Complexation and Applications in Pharmaceutical Analysis.Electrophoresis · 2026Review
- Enantioseparation of Chiral Compounds From Traditional Chinese Medicines on a Chiral Packed Capillary Column With UV Detection.Electrophoresis · 2026Article
- Recent Developments in Capillary and Microchip Electroseparations of Peptides (2023-mid 2025).Electrophoresis · 2026Review
- Cyclodextrins as Chiral Selectors in Capillary Electromigration Techniques.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Recognition Mechanisms of Chiral Selectors: An Overview.Methods in molecular biology (Clifton, N.J.) · 2026Review
- Application of Molecular Modeling to Capillary Electrophoresis Enantioseparations Promoted by Cyclodextrin-Based Chiral Selectors.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Designing Ternary Chiral DES to Enhance Enantioselectivity.ACS omega · 2025Article
- Recent Advance in Electrochemical Chiral Recognition Based on Biomaterials (2019-2024).Molecules (Basel, Switzerland) · 2025Review
- Unveiling the Power of Computational Tools in Chiral Liquid Chromatography.Molecules (Basel, Switzerland) · 2025Review
- Quantum Chemistry Based Simulation of Enantioseparation on Cyclodextrin- and Polysaccharide-Based Chiral Stationary Phases.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Insights Into the Enantioseparation of Polyhalogenated 4,4'-Bipyridines With a Cellulose Tris(3,5-Dimethylphenylcarbamate)-Based Chiral Column by Using Supercritical Fluid Chromatography.Electrophoresis · 2025Article
- Enantioseparation of Mirabegron Using Cyclodextrin-based Chiral Columns: High-performance Liquid Chromatography and Molecular Modeling Study.Journal of separation science · 2025Article
- Update on chiral recognition mechanisms in separation science.Journal of separation science · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The stereospecific analysis of chiral molecules is an important issue in many scientific fields. In separation sciences, this is achieved via the formation of transient diastereomeric complexes between a chiral selector and the selectand enantiomers driven by molecular interactions including electrostatic, ion-dipole, dipole-dipole, van der Waals or π-π interactions as well as hydrogen or halogen bonds depending on the nature of selector and selectand. Nuclear magnetic resonance spectroscopy and molecular modeling methods are currently the most frequently applied techniques to understand the selector-selectand interactions at a molecular level and to draw conclusions on the chiral separation mechanism. The present short review summarizes some of the recent achievements for the understanding of the chiral recognition of the most important chiral selectors combining separation techniques with molecular modeling and/or spectroscopic techniques dating between 2020 and early 2024. The selectors include polysaccharide derivatives, cyclodextrins, macrocyclic glycopeptides, proteins, donor-acceptor type selectors, ion-exchangers, crown ethers, and molecular micelles. The application of chiral ionic liquids and chiral deep eutectic solvents, as well as further selectors, are also briefly addressed. A compilation of all published literature on chiral selectors has not been attempted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.