Evidence map›Paper›PMID 38772591›Full record

ArticleBMJ open2024

Trends in clinical management of lactational mastitis among women attending Australian general practice: a national longitudinal study using MedicineInsight, 2011-2022.

Luke E Grzeskowiak, Aline Kunnel, Sharinne B Crawford, Meabh Cullinane, Lisa Helen Amir

Abstract read
In one paragraph

Article in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Management of Mastitis in the Hospital Setting: An International Audit Study.Journal of human lactation : official journal of International Lactation Consultant Association · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Luke E GrzeskowiakFlinders Health and Medical Research Institute, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia luke.grzeskowiak@flinders.edu.au.ORCID 0000-0001-8554-4696
Aline KunnelSAHMRI Women and Kids, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
Sharinne B CrawfordJudith Lumley Centre, School of Nursing and Midwifery, La Trobe University, Melbourne, Victoria, Australia.
Meabh CullinaneJudith Lumley Centre, School of Nursing and Midwifery, La Trobe University, Melbourne, Victoria, Australia.ORCID 0000-0003-4947-1826
Lisa Helen AmirJudith Lumley Centre, School of Nursing and Midwifery, La Trobe University, Melbourne, Victoria, Australia.ORCID 0000-0002-2510-1399

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine longitudinal trends in clinical management of lactational mastitis in women attending general practice.

designOpen cohort study.

settingAustralian general practice using data from MedicineInsight.

participantsWomen aged 18 to 44 years with one or more clinical encounters for lactational mastitis between January 2011 and July 2022. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome measure was the proportion of prescribed oral antibiotics based on the antibiotic type. Secondary outcome measures were the proportion of women prescribed other medications (eg, antifungals, lactation suppressants) or ordered selected clinical investigations including breast ultrasound, blood test, breast milk culture, nipple swab culture or breast aspirate. Outcomes were examined based on the calendar year and individual- or clinical practice-level characteristics.

resultsAmong 25 002 women who had one or more clinical encounters related to mastitis, 90.9% were prescribed oral antibiotics. While the proportion of women prescribed an oral antibiotic remained consistent from 2011 to 2022 (91.1% vs 92.5%), there were changes in the proportion receiving prescriptions for di/flucloxacillin (46.1% vs 60.4%) and cefalexin (38.6% vs 26.5%). Fewer than 12% of women were clinically investigated for their mastitis encounter, most commonly a breast ultrasound (7.1%), followed by a selected blood test (3.8%). Requests for breast milk cultures, nipple swab cultures or breast aspirates occurred in less than 1.1% of individuals. Significant increases were evident with respect to ordering of all clinical investigations, with rates at least doubling between 2011 and 2022 (6.6% vs 14.7%). Large variability in clinical management was evident according to both individual- (eg, concessional status) and clinical practice-level characteristics (eg, remoteness).

conclusionsAustralian general practitioners commonly prescribe oral antibiotics to women with mastitis and largely in line with clinical guidelines. Their use of clinical investigations as part of mastitis management has increased over the last decade.

Indexed as

Anti-Bacterial AgentsGeneral PracticeMastitisAdministration, OralAdolescentAdultAustraliaFemaleHumansLactationLongitudinal StudiesPractice Patterns, Physicians'Young AdultAnti-Bacterial AgentsEpidemiologyMICROBIOLOGYPharmacologyPrimary CarePublic health

Identifiers

PMID38772591
PMCPMC11110594

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.