Evidence map›Paper›PMID 38772530›Full record

ReviewThe world journal of men's health2025

Liquid Biomarkers in Prostate Cancer Diagnosis: Current Status and Emerging Prospects.

Yutong Liu, Koji Hatano, Norio Nonomura

Abstract readReview
In one paragraph

Review in The world journal of men's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. METCAM/MUC18 is a Biomarker and Therapeutic Target for Prostate Cancer.Asian Pacific journal of cancer prevention : APJCP · 2025
    Article
  14. Article
  15. Review
  16. Overdiagnosis and Overtreatment in Prostate Cancer.Diseases (Basel, Switzerland) · 2025
    Review
  17. Review
  18. Advancements in Biomarkers of Prostate Cancer: A Review.Technology in cancer research & treatment
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yutong LiuDepartment of Urology, Osaka University Graduate School of Medicine, Suita, Japan.ORCID https://orcid.org/0009-0009-3844-9456
Koji HatanoDepartment of Urology, Osaka University Graduate School of Medicine, Suita, Japan. koj.hatan@gmail.com.ORCID https://orcid.org/0000-0002-8409-5152
Norio NonomuraDepartment of Urology, Osaka University Graduate School of Medicine, Suita, Japan.ORCID https://orcid.org/0000-0002-6522-6233

Funding

Japan Society for the Promotion of Science 22K09447
6 · The paper itself

Abstract

Prostate cancer (PCa) is a major health concern that necessitates appropriate diagnostic approaches for timely intervention. This review critically evaluates the role of liquid biopsy techniques, focusing on blood- and urine-based biomarkers, in overcoming the limitations of conventional diagnostic methods. The 4Kscore test and Prostate Health Index have demonstrated efficacy in distinguishing PCa from benign conditions. Urinary biomarker tests such as PCa antigen 3, MyProstateScore, SelectMDx, and ExoDx Prostate IntelliScore test have revolutionized risk stratification and minimized unnecessary biopsies. Emerging biomarkers, including non-coding RNAs, circulating tumor DNA, and prostate-specific antigen (PSA) glycosylation, offer valuable insights into PCa biology, enabling personalized treatment strategies. Advancements in non-invasive liquid biomarkers for PCa diagnosis may facilitate the stratification of patients and avoid unnecessary biopsies, particularly when PSA is in the gray area of 4 to 10 ng/mL.

Indexed as

BiomarkersDiagnosisLiquid biopsyProstate-specific antigenProstatic neoplasms

Identifiers

PMID38772530
PMCPMC11704174

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.