Evidence map›Paper›PMID 38772437›Full record

ArticleNeuroscience letters2024

Basmisanil, an α5-GABA

Fernanda Daher, Narcy A Villalobos, Marcus Hanley, John R Atack, Mariana O Popa, Manoela V Fogaça

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuroscience letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Negative allosteric modulation of α5-GABAbioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fernanda DaherDepartment of Pharmacology and Physiology, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA.
Narcy A VillalobosMedicines Discovery Institute, Cardiff University, Park Place, CF10 3AT, Cardiff, Wales, United Kingdom.
Marcus HanleyMedicines Discovery Institute, Cardiff University, Park Place, CF10 3AT, Cardiff, Wales, United Kingdom.
John R AtackMedicines Discovery Institute, Cardiff University, Park Place, CF10 3AT, Cardiff, Wales, United Kingdom.
Mariana O PopaMedicines Discovery Institute, Cardiff University, Park Place, CF10 3AT, Cardiff, Wales, United Kingdom.
Manoela V FogaçaDepartment of Pharmacology and Physiology, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA. Electronic address: manoela_fogaca@urmc.rochester.edu.

Funding

Cortical GABAergic mechanisms underlying rapid and sustained antidepressant responsesR00MH126098 · NIMH · UNIVERSITY OF ROCHESTER · PI FOGACA, MANOELA · 2023 to 2025
$730k
Cortical GABAergic mechanisms underlying rapid and sustained antidepressant responsesK99MH126098 · NIMH · YALE UNIVERSITY · PI FOGACA, MANOELA · 2022 to 2022
$102k
NIMH NIH HHS K99 MH126098NIMH NIH HHS R00 MH126098
6 · The paper itself

Abstract

There is a critical need for safer and better-tolerated alternatives to address the current limitations of antidepressant treatments for major depressive disorder. Recently, drugs targeting the GABA system via α5-containing GABA

Indexed as

Antidepressive AgentsReceptors, GABA-AAnimalsBehavior, AnimalBlood-Brain BarrierBrainFemaleMaleMiceMice, Inbred C57BLMorpholinesOxazolesPyridinesAntidepressive AgentsbasmisanilGabra5 protein, mouseMorpholinesOxazolesPyridinesReceptors, GABA-AAntidepressantsBasmisanilDepressionGABA(A) receptorKetamineMajor depressive disorderMDDNegative allosteric modulatorRapid-acting antidepressantsα5-GABA(A)R

Identifiers

PMID38772437
PMCPMC11146097

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.