ArticleAddictive behaviors2024
Racial/ethnic trends in opioid and polysubstance opioid overdose mortality in adolescents and young adults, 1999-2020.
Article in Addictive behaviors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Shifting Demographics and Polysubstance Drivers of Overdose Mortality in Pennsylvania (1999-2020).Cureus · 2026Article
- Applying the Consolidated Framework for Implementation Research (CFIR) to understand college health administrator perceptions on adopting and implementing opioid overdose education and naloxone distribution (OEND) programs among universities nationally.Harm reduction journal · 2026Article
- Longitudinal associations between frequency and recency of nonmedical prescription stimulant use in adolescence and cocaine use in young adulthood.Drug and alcohol dependence · 2025Article
- The Contribution of Social and Structural Determinants of Health Deficits to Mental and Behavioral Health Among a Diverse Group of Young People.International journal of environmental research and public health · 2025Article
- Changes in Synthetic Opioid-Involved Youth Overdose Deaths in the United States: 2018-2022.Pediatrics · 2025Article
- Disparities in chronic ischemic heart disease-related mortality across sex, race, and urbanization status in the United States, 1999-2019.PLOS global public health · 2025Article
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Authors and funding
2 authors.
Funding
Abstract
objectivesPrevious reports have described variations in opioid overdose mortalities among different race/ethnicity groups. We have analyzed racial/ethnicity trends in opioid and polysubstance opioid overdose mortalities in adolescents and young adults to further characterize differences and potential sub-epidemics within this specific population.
methodsWe used mortality data from the U.S. Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research (WONDER) Multiple Cause of Death file from 1999 to 2020. Drug overdose mortalities were identified using International Classification of Diseases, Tenth Revision (ICD-10) codes. Joinpoint regression was used to examine mortality rates for all opioids, opioids with a stimulant, opioids with benzodiazepines, and opioids with alcohol among racial/ethnic groups (non-Hispanic white, non-Hispanic Black, Hispanic, non-Hispanic other) in adolescents and young adults.
resultsThe Average Annual Percent Change (AAPC) for mortality due to opioid and polysubstance opioid overdose increased for all racial/ethnic groups where data was available for analysis from 1999 to 2020. For mortality due to any opioid and any opioid with a stimulant, the greatest AAPC was seen among non-Hispanic Blacks.
conclusionsUnprecedented increases in mortality due to opioid overdose occurred in the last two decades among adolescents and young adults. Heterogenous trends support the notion that the previously defined opioid overdose epidemic "waves" may not accurately depict the effects of the crisis in all race/ethnicity groups. Additionally, alarming increases in opioid-stimulant overdose mortality starting in 2012 further characterize the interrelated effects of the third and fourth waves.
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