ArticleProbiotics and antimicrobial proteins2025
Probiotic Efficacy in Aquaculture: The Role of Technospore® (Bacillus coagulans) in Improving Nile Tilapia (Oreochromis niloticus) Performance and Disease Resistance: a Study on Gut Health, Immunological Response, and Gene Expression.
Article in Probiotics and antimicrobial proteins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- The Invisible Balance: How Prebiotics and Probiotics Can Support Fish Health and Development.Life (Basel, Switzerland) · 2026Review
- Combined effects of dietary ellagic acid and Bacillus coagulans on growth performance, antioxidant and immune responses, intestinal health, and resistance to Streptococcus agalactiae in striped catfish.Veterinary research communications · 2026Article
- Aquafeed Enrichment with Dictyota Dichotoma and Bacillus Coagulans: A Synergistic Strategy to Promote Growth, Immune Function, and Antioxidant Defensive Pathways in Cyprinus Carpio.Marine biotechnology (New York, N.Y.) · 2026Article
- Effects of supplementing diet withFrontiers in microbiology · 2026Article
- Soy Protein Concentrate Dietary Substitution andAquaculture nutrition · 2026Article
- Effects ofFrontiers in immunology · 2026Article
- Dietary oregano essential oil and sodium butyrate enhance growth, immunity, and gene expression in nile tilapia post-Aeromonas hydrophila infection.Scientific reports · 2025Article
- Effects of Microorganisms in Fish Aquaculture from a Sustainable Approach: A Review.Microorganisms · 2025Review
- Effects ofAnimals : an open access journal from MDPI · 2025Article
- Impact of Ecobiol plus ® feed additive on growth performance, physiological response, oxidative status and immunological status of Nile tilapia (Oreochromis niloticus) fingerlings challenged with Aeromonas hydrophila.BMC veterinary research · 2025Article
- Herbal essential oils improve growth, antioxidant response, and gene expression in Nile Tilapia fingerlings.Frontiers in veterinary science · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study evaluated the effects of Technospore® (Bacillus coagulans) supplementation on intestinal health, immune response, and Oreochromis niloticus (Nile tilapia) growth performance. The experiment divided fish into four groups: a control group fed an unsupplemented diet and three experimental groups receiving diets supplemented with 0.2 g/kg, 0.4 g/kg, and 0.8 g/kg of Technospore®, respectively. Results indicated that Technospore® supplementation significantly enhanced growth rates and feed efficiency in all treated groups, with the most pronounced improvements observed in the group receiving 0.4 g/kg. Furthermore, the study revealed that B. coagulans supplementation markedly boosted serum immune responses, as evidenced by increased phagocytic activity, phagocytic index, and lysozyme levels, following a challenge with Aeromonas hydrophila. Histological analysis showed improved gut morphology, while gene expression analysis indicated upregulation of immune-related genes, including liver IGF-1, GHR, HSP70, IL-1β, and TNF-α, as well as spleen TNF-α and IL-1β and intestinal C-lysozyme and TNF-α, both before and after the bacterial challenge. These findings suggest that dietary inclusion of Technospore® can significantly improve gut health and immune responses in tilapia, potentially serving as an effective prophylactic alternative to antibiotics in aquaculture.
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