Evidence map›Paper›PMID 38771420›Full record

ArticleMolecular biotechnology2025

Correlations of FCGR2A 131R/H and FCGR3A 158V/F Polymorphisms with the Susceptibility of Peri-implantitis in Chinese Han Population.

Peng Li, Bingzhuo Chen, Liang Zhao, Feng Yang, Zhu Zhang, Yuan Cao, Yang Hu

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Article in Molecular biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Peng Li *Department One of Oral and Maxillofacial Surgery, Affiliated Hospital of Tangshan Vocational and Technical College, Tangshan, 063000, China.
Bingzhuo Chen *Fifth Outpatient Department, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, 210019, China.
Liang ZhaoDepartment of Stomatology, Central Hospital Affiliated to Shenyang Medical College, No.5, Nanqizi Road, Tiexi District, Shenyang, 110026, China.
Feng YangDepartment of Stomatology, Central Hospital Affiliated to Shenyang Medical College, No.5, Nanqizi Road, Tiexi District, Shenyang, 110026, China.
Zhu ZhangDepartment of Stomatology, Central Hospital Affiliated to Shenyang Medical College, No.5, Nanqizi Road, Tiexi District, Shenyang, 110026, China.
Yuan CaoDepartment of Stomatology, Central Hospital Affiliated to Shenyang Medical College, No.5, Nanqizi Road, Tiexi District, Shenyang, 110026, China. Sycaoyuan82@163.com.ORCID http://orcid.org/0009-0006-6677-7893
Yang HuDepartment of Oral Restoration and Implantation, First Affiliated Hospital of Xinjiang Medical University/Affiliated Stomatological Hospital, Urumqi, 830054, China. Huyangdr_xj@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of the study is to investigate the relationship of peri-implantitis (PI) with FCGR2A and FCGR3A gene polymorphisms. One hundred and forty-four patients with PI and 136 patients without PI infection were selected. Gingival crevicular fluid samples were collected from the two groups. The FCGR2A and FCGR3A polymorphism in the two groups were measured. All volunteers were evaluated for periodontal status. The effect of polymorphisms on PI susceptibility was investigated by chi-square analysis and logistic regression. The frequency of FCGR2A rs1801274 GG genotype of PI group was higher than that of the control group, while the GA and AA genotype carriers were less in PI group. After adjusting for other clinical indicators, rs1801274 GA genotype, AA genotype, and the A allele were still negatively correlated with the onset of PI. FCGR3A rs396991 polymorphism was not associated with PI. FCGR2A rs1801274 polymorphism was significantly associated with PI in the Chinese Han population, and GG genotype might be a genetic risk factor for PI.

Indexed as

Genetic Predisposition to DiseasePeri-ImplantitisPolymorphism, Single NucleotideReceptors, IgGAdultAgedAllelesCase-Control StudiesChinaEast Asian PeopleFemaleGene FrequencyGenotypeHumansMaleMiddle AgedFCGR2A protein, humanFCGR3A protein, humanReceptors, IgGChinese Han populationFCGR2A rs1801274FCGR3A rs396991Peri-implantitisSusceptibility

Identifiers

PMID38771420

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.