Evidence map›Paper›PMID 38771389›Full record

ArticleJournal of robotic surgery2024

Experimental validation of the accuracy of robotic-assisted radioactive seed implantation for tumor treatment.

Zhe Ji, Zhe Wang, Yuliang Jiang, Haitao Sun, Bin Qiu, Chuang Li, Bo Liu, Qianqian Li, Leifeng Zhang, Xiangzhi Bai and 4 more

Abstract readValidation Study
PubMed Publisher
In one paragraph

Article in Journal of robotic surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Zhe Ji *Department of Radiation Oncology, Peking University Third Hospital, Beijing, China.
Zhe Wang *Department of Oncology, Affiliated Zhongshan Hospital of Dalian University, Dalian, China.
Yuliang JiangDepartment of Radiation Oncology, Peking University Third Hospital, Beijing, China.
Haitao SunDepartment of Radiation Oncology, Peking University Third Hospital, Beijing, China.
Bin QiuDepartment of Radiation Oncology, Peking University Third Hospital, Beijing, China.
Chuang LiDepartment of Oncology, Affiliated Zhongshan Hospital of Dalian University, Dalian, China.
Bo LiuImage Processing Center, Beihang University, Beijing, China.
Qianqian LiHospital of Stomatological, Cheeloo College of Medicine, Shandong University, Jinan, China.
Leifeng ZhangState Key Laboratory of Robotics and System, Harbin Institute of Technology, Harbin, China.
Xiangzhi BaiImage Processing Center, Beihang University, Beijing, China.
Ying WeiSchool of Control Science and Engineering, Shandong University, Jinan, China.
Changle LiState Key Laboratory of Robotics and System, Harbin Institute of Technology, Harbin, China.
Ruoyu Wang *Department of Oncology, Affiliated Zhongshan Hospital of Dalian University, Dalian, China. wangruoyu@dlu.edu.cn.
Junjie Wang *Department of Radiation Oncology, Peking University Third Hospital, Beijing, China. junjiewang_edu@sina.cn.

Funding

Innovation and Transformation Fund of Peking University Third Hospital BYSYZHKC2021117Liaoning Province Science and Technology Department Grant 2021JH1/10400051National Key Clinical Specialty Discipline Construction Program of China 2021National Key Research and Development Program of China 2019YFB1311300, 2019YFB1311305
6 · The paper itself

Abstract

An experimental validation of a robotic system for radioactive iodine-125 seed implantation (RISI) in tumor treatment was conducted using customized phantom models and animal models simulating liver and lung lesions. The robotic system, consisting of planning, navigation, and implantation modules, was employed to implant dummy radioactive seeds into the models. Fiducial markers were used for target localization. In phantom experiments across 40 cases, the mean errors between planned and actual seed positions were 0.98 ± 1.05 mm, 1.14 ± 0.62 mm, and 0.90 ± 1.05 mm in the x, y, and z directions, respectively. The x, y, and z directions correspond to the left-right, anterior-posterior, and superior-inferior anatomical planes. Silicone phantoms exhibiting significantly smaller x-axis errors compared to liver and lung phantoms (p < 0.05). Template assistance significantly reduced errors in all axes (p < 0.05). No significant dosimetric deviations were observed in parameters such as D90, V100, and V150 between plans and post-implant doses (p > 0.05). In animal experiments across 23 liver and lung cases, the mean implantation errors were 1.28 ± 0.77 mm, 1.66 ± 0.69 mm, and 1.86 ± 0.93 mm in the x, y, and z directions, slightly higher than in phantoms (p < 0.05), with no significant differences between liver and lung models. The dosimetric results closely matched planned values, confirming the accuracy of the robotic system for RISI, offering new possibilities in clinical tumor treatment.

Indexed as

Iodine RadioisotopesLung NeoplasmsPhantoms, ImagingRobotic Surgical ProceduresAnimalsBrachytherapyFiducial MarkersHumansLiver NeoplasmsIodine-125Iodine RadioisotopesAccuracyExperimental validationRadioactive seed implantationRobotTemplate

Identifiers

PMID38771389

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.