Evidence map›Paper›PMID 38771351›Full record

ArticleSocial psychiatry and psychiatric epidemiology2024

The association between sexual orientation and psychotic like experiences during adolescence: a prospective cohort study.

Emma Corcoran, Amal Althobaiti, Glyn Lewis, Francesca Solmi, Tayla McCloud, Gemma Lewis

Abstract read
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Article in Social psychiatry and psychiatric epidemiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Emma CorcoranThe Oxford Institute of Clinical Psychology Training and Research, The Oxford Centre for Psychological Health, Isis Education Centre, Warneford Hospital, Oxford, OX3 7JX, UK.
Amal AlthobaitiDivision of Psychiatry, University College London, Maple House, 149 Tottenham Court Road, London, W17 7NF, UK.
Glyn LewisDivision of Psychiatry, University College London, Maple House, 149 Tottenham Court Road, London, W17 7NF, UK.
Francesca SolmiDivision of Psychiatry, University College London, Maple House, 149 Tottenham Court Road, London, W17 7NF, UK.
Tayla McCloudDivision of Psychiatry, University College London, Maple House, 149 Tottenham Court Road, London, W17 7NF, UK.
Gemma LewisDivision of Psychiatry, University College London, Maple House, 149 Tottenham Court Road, London, W17 7NF, UK. gemma.lewis@ac.uk.

Funding

Wellcome TrustWellcome Trust and Royal Society 223248/Z/21/Z
6 · The paper itself

Abstract

purposePsychotic like experiences (PLEs) are relatively common during adolescence and associated with a range of negative outcomes. There is evidence that sexual minorities are at increased risk of mental health problems including depression, anxiety, self-harm and suicidality. However, no study has investigated the association between sexual orientation and psychotic experiences during adolescence. We compared trajectories of PLEs in sexual minority and heterosexual adolescents from 12 to 24 years of age.

methodsWe used data from the Avon Longitudinal Study of Parents and Children (ALSPAC). Participants provided data on sexual orientation at age 16 and PLEs at ages 12, 17 and 24. We used multi-level logistic regression models to test associations between sexual orientation and PLEs, before and after adjusting for covariates. We investigated whether the association differed according to time-point and sex using interaction terms.

resultsWe found evidence that the odds of PLEs were 2.35 times (95% Confidence Interval 1.79-3.06, p < 0.0001) higher among sexual minority compared with heterosexual adolescents, across all ages, after adjusting for covariates. There was no evidence that the association between sexual orientation and PLEs differed according to time-point (p = 0.50) or sex (p = 0.29).

conclusionWe found an increased risk of psychosis in sexual minorities compared with heterosexuals, which was present from around 12 years of age and persisted until age 24. Early interventions to prevent this mental health inequality could include universal interventions to promote inclusivity and acceptance of diverse sexual orientations.

Indexed as

Psychotic DisordersSexual and Gender MinoritiesSexual BehaviorAdolescentChildFemaleHeterosexualityHumansLogistic ModelsLongitudinal StudiesMaleProspective StudiesRisk FactorsYoung AdultAdolescenceALSPACPsychotic experiencesSexual orientation

Identifiers

PMID38771351
PMCPMC11522136

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.