Evidence map›Paper›PMID 38771057›Full record

ArticlemSphere2024

The trophoblast surface becomes refractory to adhesion by congenitally transmitted

Rafaela J da Silva, Leah F Cabo, Jada L George, Laty A Cahoon, Liheng Yang, Carolyn B Coyne, Jon P Boyle

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSphere, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rafaela J da SilvaDepartment of Biological Sciences, Dietrich School of Arts, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-6772-4658
Leah F CaboDepartment of Biological Sciences, Dietrich School of Arts, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Jada L GeorgeDepartment of Biological Sciences, Dietrich School of Arts, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Laty A CahoonDepartment of Biological Sciences, Dietrich School of Arts, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-2061-319X
Liheng YangDepartment of Integrative Immunobiology, Duke University School of Medicine, Durham, North Carolina, USA.
Carolyn B CoyneDepartment of Integrative Immunobiology, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0002-1884-6309
Jon P BoyleDepartment of Biological Sciences, Dietrich School of Arts, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-0000-9243

Funding

Placental resistance and response to the teratogenic pathogen Toxoplasma gondiiR01HD106247 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Jon P Boyle, Carolyn B Coyne · 2022 to 2026
$2.8M
Molecular mechanisms of Toxoplasma-placenta interactionsR21AI139576 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BOYLE, JON P, COYNE, CAROLYN B · 2018 to 2019
$430k
NIAID NIH HHS R21 AI139576NICHD NIH HHS R01 HD106247
6 · The paper itself

Abstract

The placenta is a critical barrier against viral, bacterial, and eukaryotic pathogens. For most teratogenic pathogens, the precise molecular mechanisms of placental resistance are still being unraveled. Given the importance of understanding these mechanisms and challenges in replicating trophoblast-pathogen interactions using

Indexed as

Listeria monocytogenesToxoplasmaTrophoblastsCell AdhesionFemaleHumansPlacentaPregnancyStem CellsToxoplasmosiscytotrophoblasthuman trophoblast stem cellsListeria monocytogenessyncytiotrophoblastToxoplasma gondiitranscriptome

Identifiers

PMID38771057
PMCPMC11332349

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.