Evidence map›Paper›PMID 38771048›Full record

ArticleAmerican journal of respiratory and critical care medicine2024

Airway-occluding Mucus Plugs and Cause-specific Mortality in Chronic Obstructive Pulmonary Disease.

Sofia K Mettler, Sushilkumar Sonavane, Scott Grumley, Hrudaya P Nath, Andrew C Yen, Carrie Pistenmaa, Pietro Nardelli, Raul San Jose Estepar, Michael H Cho, Alejandro A Diaz

Abstract readLetter
In one paragraph

Article in American journal of respiratory and critical care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Mucus Plugs and Eosinophilic Inflammation: Expanding the Paradigm to COPD.The journal of allergy and clinical immunology. In practice · 2026
    Review
  6. Molecular echoes of mucus plugging in chronic obstructive pulmonary disease.American journal of respiratory and critical care medicine · 2026
    Article
  7. Mucus plugs-associated gene expression identifies pathophysiology shared with chronic bronchitis.American journal of respiratory and critical care medicine · 2026
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sofia K MettlerDepartment of Medicine, Mount Auburn Hospital, Cambridge, Massachusetts.ORCID 0000-0002-7553-1346
Sushilkumar SonavaneDepartment of Radiology, Mayo Clinic, Jacksonville, Florida.
Scott GrumleyDepartment of Radiology, University of Alabama at Birmingham, Birmingham, Alabama; and.
Hrudaya P NathDepartment of Radiology, University of Alabama at Birmingham, Birmingham, Alabama; and.
Andrew C YenDepartment of Radiology, University of California San Diego, San Diego, California.
Carrie PistenmaaDivision of Pulmonary and Critical Care Medicine, and.
Pietro NardelliDepartment of Radiology, Brigham and Women's Hospital, Boston, Massachusetts.
Raul San Jose EsteparDepartment of Radiology, Brigham and Women's Hospital, Boston, Massachusetts.ORCID 0000-0002-3677-1996
Michael H ChoChanning Division of Network Medicine.
Alejandro A DiazDivision of Pulmonary and Critical Care Medicine, and.ORCID 0000-0001-5037-2919

Funding

Genetic Epidemiology of COPDU01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2007 to 2021
$56.9M
Genetic Epidemiology of COPDU01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2007 to 2021
$20.7M
Clinical Implications, Genomics, and Transcriptions of Mucus Plugging in SmokersR01HL149861 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CHO, MICHAEL H., DIAZ, ALEJANDRO · 2020 to 2023
$3.2M
Prognostic Markers of Emphysema ProgressionR01HL149877 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SAN JOSE ESTEPAR, RAUL · 2020 to 2023
$2.8M
Understanding airway mucus dysfunction in population-based studiesR01HL164824 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI DIAZ, ALEJANDRO · 2022 to 2025
$2.7M
The Pulmonary Vasculature and Platelets in Emphysema and COPDK23HL141651 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI PISTENMAA, CARRIE L · 2019 to 2023
$983k
COPD FoundationNHLBI NIH HHS K23 HL141651NHLBI NIH HHS R01 HL149861NHLBI NIH HHS R01-HL149861NHLBI NIH HHS R01 HL149877NHLBI NIH HHS R01 HL164824NHLBI NIH HHS R01-HL164824NHLBI NIH HHS U01 HL089856NHLBI NIH HHS U01 HL089897
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MucusPulmonary Disease, Chronic ObstructiveAgedCause of DeathFemaleHumansMaleMiddle Aged

Identifiers

PMID38771048
PMCPMC11208961

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.