Evidence map›Paper›PMID 38771046›Full record

ArticlemBio2024

Immunological and microbial shifts in the aging rhesus macaque lung during nontuberculous mycobacterial infection.

Isaac R Cinco, Ethan G Napier, Nicholas S Rhoades, Michael H Davies, Derek B Allison, Steven G Kohama, Luiz Bermudez, Kevin Winthrop, Cristina Fuss, Eliot R Spindel and 1 more

Abstract read
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Short-Term Alcohol Consumption Is Sufficient to Disrupt Microbial Communities and the Intestinal and Circulating Metabolites in a Non-Human Primate Model.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Advances in Single-Cell Sequencing for Infectious Diseases: Progress and Perspectives.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Isaac R Cinco *Department of Microbiology, Immunology, and Molecular Genetics, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.
Ethan G Napier *Department of Microbiology, Immunology, and Molecular Genetics, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.
Nicholas S Rhoades *Department of Microbiology, Immunology, and Molecular Genetics, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.
Michael H DaviesDivision of Neuroscience, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, USA.
Derek B AllisonDepartment of Pathology and Laboratory Medicine, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.
Steven G KohamaDivision of Neuroscience, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, USA.
Luiz BermudezDepartment of Microbiology, College of Sciences, Oregon State University, Corvallis, Oregon, USA.
Kevin WinthropDivision of Infectious Diseases, School of Medicine, Oregon Health and Science University, Portland, Oregon, USA.
Cristina FussDepartment of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Connecticut, USA.
Eliot R SpindelDivision of Neuroscience, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, USA.
Ilhem MessaoudiDepartment of Microbiology, Immunology, and Molecular Genetics, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.ORCID 0000-0003-3203-2405

Funding

Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9M
University of Kentucky Markey Cancer Center Support Grant ECIA SupplementP30CA177558 · NCI · UNIVERSITY OF KENTUCKY · PI Jennifer F Rogers · 2013 to 2026
$38.3M
Mechanisms of increased susceptibility to pulmonary Nontuberculous Mycobacterial disease in the elderlyR01AI152258 · NIAID · UNIVERSITY OF KENTUCKY · PI MESSAOUDI, ILHEM · 2020 to 2024
$3.5M
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) 5R01AI152258-05NCI NIH HHS P30 CA177558NIAID NIH HHS R01 AI152258NIH HHS P51 OD011092
6 · The paper itself

Abstract

Nontuberculous mycobacteria (NTM) are environmentally ubiquitous organisms that predominately cause NTM pulmonary disease (NTMPD) in individuals over the age of 65. The incidence of NTMPD has increased in the U.S., exceeding that of IMPORTANCE: Nontuberculous mycobacteria (NTM) are emerging as pathogens of high consequence, as cases of NTM pulmonary disease (NTMPD) have exceeded those of

Indexed as

LungMacaca mulattaMycobacterium Infections, NontuberculousAge FactorsAnimalsFemaleMaleMicrobiotaMycobacteriumTomography, X-Ray ComputedTranscriptomeaginglunglung immunologyM. avium complexmicrobiomerhesus macaquesingle-cell RNA sequencing

Identifiers

PMID38771046
PMCPMC11237422

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.