Evidence map›Paper›PMID 38771031›Full record

ArticleAntimicrobial agents and chemotherapy2024

Antimalarial resistance risk in Mozambique detected by a novel quadruplex droplet digital PCR assay.

Noah Brown, Clemente da Silva, Caroline Webb, Daniela Matias, Brigite Dias, Beatriz Cancio, Miguel Silva, Ruben Viegas, Crizolgo Salvador, Nordino Chivale and 6 more

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Mapping Antimalarial Drug Resistance in Mozambique: A Systematic Review ofInternational journal of molecular sciences · 2024
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Noah Brown *Department of Biology, University of Virginia, Charlottesville, Virginia, USA.
Clemente da Silva *Global Health and Tropical Medicine, GHTM, Associate Laboratory in Translation and Innovation Towards Global Health, LA-REAL, Instituto de Higiene e Medicina Tropical, IHMT, Universidade NOVA de Lisboa, UNL, Lisbon, Portugal.ORCID 0000-0003-2083-2579
Caroline Webb *Department of Biology, University of Virginia, Charlottesville, Virginia, USA.
Daniela MatiasGlobal Health and Tropical Medicine, GHTM, Associate Laboratory in Translation and Innovation Towards Global Health, LA-REAL, Instituto de Higiene e Medicina Tropical, IHMT, Universidade NOVA de Lisboa, UNL, Lisbon, Portugal.
Brigite DiasGlobal Health and Tropical Medicine, GHTM, Associate Laboratory in Translation and Innovation Towards Global Health, LA-REAL, Instituto de Higiene e Medicina Tropical, IHMT, Universidade NOVA de Lisboa, UNL, Lisbon, Portugal.
Beatriz CancioGlobal Health and Tropical Medicine, GHTM, Associate Laboratory in Translation and Innovation Towards Global Health, LA-REAL, Instituto de Higiene e Medicina Tropical, IHMT, Universidade NOVA de Lisboa, UNL, Lisbon, Portugal.
Miguel SilvaGlobal Health and Tropical Medicine, GHTM, Associate Laboratory in Translation and Innovation Towards Global Health, LA-REAL, Instituto de Higiene e Medicina Tropical, IHMT, Universidade NOVA de Lisboa, UNL, Lisbon, Portugal.
Ruben ViegasGlobal Health and Tropical Medicine, GHTM, Associate Laboratory in Translation and Innovation Towards Global Health, LA-REAL, Instituto de Higiene e Medicina Tropical, IHMT, Universidade NOVA de Lisboa, UNL, Lisbon, Portugal.
Crizolgo SalvadorInstituto Nacional de Saúde, Maputo (INS), Maputo, Mozambique.
Nordino ChivaleInstituto Nacional de Saúde, Maputo (INS), Maputo, Mozambique.
Sonia LuisHospital Provincial de Matola, Matola, Mozambique.
Paulo ArnaldoInstituto Nacional de Saúde, Maputo (INS), Maputo, Mozambique.
Julia ZulawinskaDepartment of Biology, University of Virginia, Charlottesville, Virginia, USA.
Christopher C MooreDivision of Infectious Disease and International Health, University of Virginia, Charlottesville, Virginia, USA.
Fatima NogueiraGlobal Health and Tropical Medicine, GHTM, Associate Laboratory in Translation and Innovation Towards Global Health, LA-REAL, Instituto de Higiene e Medicina Tropical, IHMT, Universidade NOVA de Lisboa, UNL, Lisbon, Portugal.ORCID 0000-0003-0313-0778
Jennifer L GulerDepartment of Biology, University of Virginia, Charlottesville, Virginia, USA.ORCID 0000-0001-6301-4563

Funding

The evolution of copy number variations in the AT-rich Plasmodium genomeR01AI150856 · NIAID · UNIVERSITY OF VIRGINIA · PI GULER, JENNIFER LYNN · 2021 to 2025
$2.0M
Center for Global Health Equity (UVA)Fundacao Millennium BCPFundacao para a Ciencia e a TecnologiaGlobal Infectious Disease Institute (UVA)HHS | National Institutes of Health (NIH) R01AI150856Instituto Camoes Bolsas CamoesNIAID NIH HHS R01 AI150856Paroquia de Sao Nicolau-Lisboa
6 · The paper itself

Abstract

While the

Indexed as

AntimalarialsDNA Copy Number VariationsDrug ResistanceMalaria, FalciparumPlasmodium falciparumProtozoan ProteinsAmodiaquineArtemisininsAspartic Acid EndopeptidasesATP-Binding Cassette, Sub-Family C ProteinsHumansLumefantrineMozambiquePiperazinesPolymerase Chain ReactionQuinolinesAmodiaquineAntimalarialsArtemisininsAspartic Acid EndopeptidasesATP-Binding Cassette, Sub-Family C ProteinsLumefantrineMdr1 protein, Plasmodium falciparumpiperaquinePiperazinesplasmepsin IIProtozoan ProteinsQuinolinescopy number variationdroplet digital PCRdrug resistancemalariamultidrug resistanceplasmepsin

Identifiers

PMID38771031
PMCPMC11232384

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.