ArticleHead & neck2024
Skull base surgery for malignant tumors: The 2nd international collaborative study (1995-2015).
Article in Head & neck, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Use of Free Flaps in the Reconstruction of the Ventral Skull Base: A Systematic Literature Review.Head & neck · 2026Pooled it
- Surgical margin assessment and prognostic impact in sinonasal cancers: a systematic review and meta-analysis.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2025Pooled it
- Unveiling an Untold Legacy: The History of the North American Skull Base Society from the Recollections of Early Presidents.Journal of neurological surgery. Part B, Skull base · 2026Review
- Article
- Endoscopic Endonasal Approach for Surgical Treatment of Nasal and Ethmoidal Malignancies: A Retrospective Multicenter Study.Therapeutic advances in allergy and rhinologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
50 authors.
Funding
Abstract
backgroundThe current study presents the effort of a global collaborative group to review the management and outcomes of malignant tumors of the skull base worldwide. PATIENTS AND
methodsA total of 28 institutions contributed data on 3061 patients. Analysis evaluated clinical variables, survival outcomes, and multivariable factors associated with outcomes.
resultsThe median age was 56 years (IQR 44-67). The open surgical approach was used in 55% (n = 1680) of cases, endoscopic resection was performed in 36% (n = 1087), and the combined approach in 9.6% (n = 294). With a median follow-up of 7.1 years, the 5-year OS DSS and RFS were 65%, 71.7% and 53%, respectively. On multivariable analysis, older age, comorbidities, histology, dural/intracranial involvement, positive margins, advanced stage, and primary site were independent prognostic factors for OS, DSS, and RFS. Adjuvant RT was a protective prognostic factor.
conclusionThe progress across various disciplines may have contributed to improved OS and DSS in this study compared to previous reports.
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Registered trials
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