Evidence map›Paper›PMID 38770844›Full record

ArticleIranian biomedical journal2024

Facile Green Synthesis of Iron Oxide Nanoparticles and Their Impact on Cytotoxicity, Antioxidative Properties and Bactericidal Activity.

Sejal S Shah, Bhavika P. Turakhia, Nihar Purohit, Khushal M. Kapadiya, Chita R. Sahoo, Akhilesh Prajapati

Abstract read
In one paragraph

Article in Iranian biomedical journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Biogenic α-FeDiscover nano · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sejal S ShahDepartment of Bioinformatics, Faculty of Technology, Marwadi University, Rajkot, Gujarat, India.
Bhavika P. TurakhiaDepartment of Bioinformatics, Faculty of Technology, Marwadi University, Rajkot, Gujarat, India.
Nihar PurohitDepartment of Life Sciences, Biotechnology Division, School of Science, GSFC University, Vadodara-391750, Gujarat, India.
Khushal M. KapadiyaSchool of Science, Department of Chemistry, RK University, Rajkot, Gujarat, India.
Chita R. SahooCentral Research Laboratory, Institute of Medical Sciences & SUM Hospital, Siksha O Anusandhan Deemed to be University, Bhubaneswar 751003, Odisha, India.
Akhilesh PrajapatiDepartment of Life Sciences, Biotechnology Division, School of Science, GSFC University, Vadodara-391750, Gujarat, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Bioreductive processes are quite potent, effective and affordable for the synthesis of green nanoparticles (NPs), as compared to the physical and chemical methods. The present study aimed to evaluate the bactericidal, antioxidative and anticancer activity of turmeric rhizome-iron oxide nanoparticles (FeONPs) derived from the turmeric rhizome (Curcuma amada) using ferric chloride as a precursor. Methods: With focusing on the manufacture of FeONPs via green approach, we characterized the NPs using FTIR, FT-Vis, DLS, and UV-Vis spectroscopy. The produced particles were tested for antibacterial, antioxidant, and anticancer properties. The synthesized NPs were also examined using the MDA-MB-231 human epithelial breast cancer cell line and NCI-60 cancer cell lines. Results: The antioxidant activity of TR-FeONPs was concentration-dependent. The scavenging activity of TR-FeONPs was 76.09% at a concentration of 140 µg/ml. Using different concentrations of TR-FeONPs in the MTT assay against the MDA-MB-231 cell line indicated a reduction of less than 50% in cell viability at 125 µg/ml. Moreover, TR-FeONPs exhibited an effective bactericidal property. The gTR-FeONPs synthesized bioreductively were found to be effective in renal cancer, UO-31 cell line, with GI50 value of 66.64%. Conclusion: Our study showcases a sustainable method based on green chemistry principles to produce FeONPs utilizing turmeric rhizome. We anticipate that the FeONPs produced through this biosynthesis process could serve as a promising drug delivery system in cancer treatment and as an effective antimicrobial agent against various diseases.

Indexed as

Anti-Bacterial AgentsAntioxidantsGreen Chemistry TechnologyAnimalsFerric CompoundsHumansMagnetic Iron Oxide NanoparticlesMicrobial Sensitivity TestsAnti-Bacterial AgentsAntioxidantsFerric Compoundsferric oxideAntioxidantsBactericidale activityGreen SynthesisMDA-MB-231cellsMolecular docking

Identifiers

PMID38770844
PMCPMC11186612

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.