Evidence map›Paper›PMID 38770343›Full record

ArticleHeliyon2024

Association between sleep duration and serum neurofilament light chain levels among adults in the United States.

Jiaxing Liang, Tengchi Ma, Youlei Li, Ruixin Sun, Shuaishuai Zhao, Yuzhe Shen, Hui Gao, Yunhang Jing, Xinyue Bai, Mengze He and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Non-linear associations between sleep duration and plasma p-tau181 in the Framingham Heart Study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jiaxing LiangMedical School of Yan'an University, Yan'an, China.
Tengchi MaMedical School of Yan'an University, Yan'an, China.
Youlei LiMedical School of Yan'an University, Yan'an, China.
Ruixin SunMedical School of Yan'an University, Yan'an, China.
Shuaishuai ZhaoMedical School of Yan'an University, Yan'an, China.
Yuzhe ShenMedical School of Yan'an University, Yan'an, China.
Hui GaoMedical School of Yan'an University, Yan'an, China.
Yunhang JingMedical School of Yan'an University, Yan'an, China.
Xinyue BaiMedical School of Yan'an University, Yan'an, China.
Mengze HeMedical School of Yan'an University, Yan'an, China.
Qingyan WangMedical School of Yan'an University, Yan'an, China.
Huilin XiMedical School of Yan'an University, Yan'an, China.
Rui ShiDepartment of Geriatrics Cardiology, The Second Affiliated Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an, China.
Yanling YangMedical School of Yan'an University, Yan'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Neurofilaments are neuron specific skeleton proteins maintaining axon transduction speed, leaked into cerebrospinal fluid and serum after axonal injury or neuron death. Sleep duration change has long related to many health issues but lack laboratory examination. Methods: This study enrolled total 10,175 participants from 2013 to 2014 National Health and Nutrition Examination Survey and used a multi-variable linear model to analyze the relationship between sleep duration and serum neurofilament light chain (sNfL) level. Results: There was a fixed relationship between sleep duration and sNfL level (β = 0.65, Conclusion: In summary, there was a J-shaped relationship between sleep duration and sNfL level in the United States of America representative group, these may suggest that extreme sleep duration can be deleterious judged by sNfL level. And still need large cohort study to determine the accurate relationship, and cluster analysis to infer the nervous disease connected with extreme sleep duration.

Indexed as

Cross-sectional studyNeuron damageSerum neurofilament light chainSleep qualityTrouble sleeping

Identifiers

PMID38770343
PMCPMC11103434

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.