ArticleJACC. Advances2024
Sex and Age Characteristics in Acute or Chronic Myocarditis A Descriptive, Multicenter Cohort Study.
Article in JACC. Advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Acute and Chronic Myocarditis in Men and Women.Current heart failure reports · 2026Review
- Time-Critical Cardiovascular Risk After COVID-19: A Population-Based Analysis Across Variant Eras.Mayo Clinic proceedings. Innovations, quality & outcomes · 2026Article
- Importance of integrating biological sex and age analyses in health research.Biology of sex differences · 2026Article
- T Cell Receptor Repertoires Across the Continuum of Vascular, Myocardial, and Age-Related Diseases.Immunological reviews · 2026Review
- Sex matters: mechanistic insights into sex-driven patterns of autoimmunity and implications for pharmacotherapy.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- Global epidemiology of myocarditis: disparities in age, sex and geography.Nature reviews. Cardiology · 2026Review
- Monocyte Titin Gene Expression as a Biomarker of Left Ventricular Dysfunction in Acute Myocarditis.Genes · 2026Article
- Whole-heart 3D reconstruction of mouse CVB3 myocarditis reveals spatial and transcriptomic heterogeneity of immune foci.Cardiovascular research · 2025Article
- Mapping myocarditis in three dimensions.Cardiovascular research · 2025Article
- Review
- Incidence and burden of myocarditis in the Middle East and North Africa: a secondary analysis of global burden of diseases study 2019.BMC cardiovascular disorders · 2025Article
- High-sensitivity troponin T as a rule-out marker for myocardial inflammation detectable by CMR imaging.Open heart · 2025Article
- A comparative review of myocarditis in pediatrics versus adults: pathogenesis, diagnosis, and management.Frontiers in immunology · 2025Review
- Changing Epidemiology of Myocarditis in Australia: A Population-Based Cohort Study.Journal of clinical medicine · 2024Article
- Myocarditis Associated with COVID-19 Vaccination.Vaccines · 2024Review
- Mechanisms underlying sex differences in autoimmunity.The Journal of clinical investigation · 2024Review
- Understanding Myocarditis: From an Early Sketch Toward a More Complete Picture.JACC. Advances · 2024Article
- Editorial: Extracorporeal cardio-pulmonary resuscitation (ECPR).Frontiers in cardiovascular medicine · 2024Article
Corrections and comments
- Commented on by
Authors and funding
16 authors.
Funding
Abstract
backgroundUnderstanding the clinical features of myocarditis in various age groups is required to identify age-specific disease patterns.
objectivesThe objective of this study was to examine differences in sex distribution and clinical outcomes in patients with myocarditis of various ages.
methodsPatients with acute or chronic myocarditis in 3 centers in Berlin, Germany from 2005 to 2021 and in the United States (National Inpatient Sample) from 2010 to 2019 were included. Age groups examined included "prepubescent" (below 11 years for females and below 13 years for males), adolescents (11 [female] or 13 [male] to 18 years), young adults (18-35 years), "middle-aged adults" (35-54 years), and older adults (age >54 years). In patients admitted to the hospital, hospital mortality, length of stay, and medical complication rates were examined.
resultsOverall, 6,023 cases in Berlin and 9,079 cases in the U.S. cohort were included. In both cohorts, there were differences in sex distribution among the 5 age categories, and differences in the distribution were most notable in adolescents (69.3% males vs 30.7% females) and in young adults (73.8% males vs 26.3% females). Prepubescent and older adults had the highest rates of in-hospital mortality, hospital length of stay, and medical complications. In the Berlin cohort, prepubescent patients had higher levels of leukocytes (
conclusionsIn this study, we found that sex differences in myocarditis and clinical features of myocarditis were age-dependent.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.