Evidence map›Paper›PMID 38770172›Full record

ArticleJournal of multidisciplinary healthcare2024

Aspartate Aminotransferase-to-Platelet Ratio Index (APRI) as a Novel Score in Early Detection of Complicated Dengue Fever.

Zubia Jamil, Samreen Khalid, Hafiz Muhammad Manan Haider Khan, Ikram Waheed, Amna Ehsan, Mohammed Alissa, Khalid Muhammad, Nayla Munawar, Yasir Waheed

Abstract read
In one paragraph

Article in Journal of multidisciplinary healthcare, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zubia JamilDepartment of Medicine, Foundation University School of Health Sciences, Foundation University, Islamabad, 44000, Pakistan.
Samreen KhalidDepartment of Medicine, Foundation University School of Health Sciences, Foundation University, Islamabad, 44000, Pakistan.
Hafiz Muhammad Manan Haider KhanDepartment of Rehabilitation Sciences, Shifa Tameer-E-Millat University, Islamabad, 44000, Pakistan.ORCID 0000-0002-0223-7533
Ikram WaheedDepartment of Medicine, Foundation University School of Health Sciences, Foundation University, Islamabad, 44000, Pakistan.
Amna EhsanDepartment of Medicine, Foundation University School of Health Sciences, Foundation University, Islamabad, 44000, Pakistan.
Mohammed AlissaDepartment of Medical Laboratory, College of Applied Medical Sciences, Prince Sattam Bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia.
Khalid MuhammadDepartment of Biology, College of Science, UAE University, Al Ain, 15551, United Arab Emirates.ORCID 0000-0001-6488-1722
Nayla MunawarDepartment of Chemistry, College of Science, UAE University, Al Ain, 15551, United Arab Emirates.
Yasir WaheedGilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos, 1401, Lebanon.ORCID 0000-0002-5789-4215

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The occurrence of dengue fever presents a considerable burden for public health care in developing countries. This study aims to validate APRI as predictor score for severity of dengue fever so that catastrophic events could be prevented, and early triage can save lives. Methods: The retrospective cross-sectional study was done on dengue positive patients from August to November 2023. APRI score was calculated for every patient at the time of admission. The primary end-point was Results: The mean APRI score of 135 patients was 20.06 ± 6.31. AUC for APRI score was 0.93 (p < 0.0001) indicating that APRI score calculated at the time of admission is an excellent marker in determining the complicated dengue. The cut-off value for APRI score was 9.04 (sensitivity 84.91%, specificity 89.02%, p < 0.0001). The patients with APRI <9.04 mostly developed simple dengue fever (54.1%) vs DHF (4.4%) and DSS (1.5%), while patients with APRI >9.04 had more DHF (20.7%) and DSS (12.6%) vs simple dengue fever (6.7%). None of the patient died with APRI <9.04 while the mortality rate was 3.7% in patients with APRI >9.04. Conclusion: The APRI score, calculated at the time of admission, is an excellent marker in determining the severe dengue.

Indexed as

area under curveaspartate aminotransferasedenguedengue hemorrhagic feverROC curvesevere dengue

Identifiers

PMID38770172
PMCPMC11104365

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