Evidence map›Paper›PMID 38769982›Full record

ArticleTransplantation direct2024

Deceased Donors With HIV in the Era of the HOPE Act: Referrals and Procurement.

Tao Liang, Jordan H Salas, Mary G Bowring, Oyinkan Kusemiju, Brittany Barnaba, Matthew Wingler, Deborah McRann, Alghidak Salama, R Patrick Wood, Allan Massie and 4 more

Abstract read
In one paragraph

Article in Transplantation direct, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Potential pool of cardiothoracic organs from donors with HIV.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Tao LiangDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
Jordan H SalasDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
Mary G BowringDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
Oyinkan KusemijuDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
Brittany BarnabaDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
Matthew WinglerClinical Resource Solutions, LLC, Quincy, IN.
Deborah McRannInfinite Legacy, Baltimore, MD.
Alghidak SalamaDepartment of Surgery, Miller School of Medicine, University of Miami, Miami, FL.
R Patrick WoodLifeGift Organ Procurement Organization, Houston, TX.
Allan MassieDepartment of Surgery, New York University Grossman School of Medicine, New York, NY.
William WerbelDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
Aaron A R TobianDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD.
Dorry L SegevDepartment of Surgery, New York University Grossman School of Medicine, New York, NY.
Christine M DurandDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.ORCID https://orcid.org/0000-0003-2605-9257

Funding

HOPE in Action: A Clinical Trial of HIV-to-HIV Liver TransplantationU01AI138897 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Christine Marie Durand, DORRY L. SEGEV · 2018 to 2026
$25.5M
HOPE in Action: A clinical trial of HIV-to-HIV deceased donor kidney transplantationU01AI134591 · NIAID · JOHNS HOPKINS UNIVERSITY · PI DURAND, CHRISTINE MARIE, SEGEV, DORRY L. · 2017 to 2021
$11.0M
Unlocking the Potential of HIV-Infected Deceased Donors for Organ TransplantationR01AI120938 · NIAID · JOHNS HOPKINS UNIVERSITY · PI TOBIAN, AARON A · 2016 to 2021
$4.3M
Continuous allocation score design for guaranteeing equity and reducing discards in kidney and liver transplantationR01DK132395 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Allan B Massie · 2023 to 2026
$2.7M
Patient Oriented Research in Solid Organ TransplantationK24AI144954 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SEGEV, DORRY L. · 2020 to 2024
$956k
The Landscape of Serious Infections following Kidney Transplantation in People Living with HIVK23AI157893 · NIAID · JOHNS HOPKINS UNIVERSITY · PI WERBEL, WILLIAM · 2021 to 2025
$847k
Leveraging a novel health records platform to predict the development of cardiovascular disease following kidney transplantationF30HL168842 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI BOWRING, MARY GRACE · 2023 to 2025
$170k
NHLBI NIH HHS F30 HL168842NIAID NIH HHS K23 AI157893NIAID NIH HHS K24 AI144954NIAID NIH HHS R01 AI120938NIAID NIH HHS U01 AI134591NIAID NIH HHS U01 AI138897NIDDK NIH HHS R01 DK132395
6 · The paper itself

Abstract

Background: The HIV Organ Policy Equity Act legalizes organ procurement from donors with HIV (HIV D+). A prior survey of Organ Procurement Organizations (OPOs) estimated >2000 HIV D+ referrals/year; however, only 30-35 HIV D+/year have had organs procured. Given this gap, we sought to understand HIV D+ referrals and procurements in practice. Methods: We prospectively collected data on all OPO-reported HIV D+ referrals, including reasons for nonprocurement. We evaluated trends and compared HIV D+ characteristics by procurement status using regression, chi-squared tests, and Wilcoxon rank-sum tests. Results: From December 23, 2015 to May 31, 2021, there were 710 HIV D+ referrals from 49 OPOs, of which 171 (24%) had organs procured. HIV D+ referrals increased from 7 to 15 per month ( Conclusions: In the early years of the HIV Organ Policy Equity Act, actual HIV D+ referrals were much lower than prior estimates; however, the numbers and procurement rates increased over time. Nonprocurement was attributed to both medical and nonmedical issues, and addressing these issues could increase organ availability.

Identifiers

PMID38769982
PMCPMC11104717

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.