ArticleJournal of Korean medical science2024
Clinical Characteristics and Frequency of Chronic Obstructive Pulmonary Disease Exacerbations in Korean Patients: Findings From the KOCOSS Cohort 2012-2021.
Article in Journal of Korean medical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05750810 (Exacerbations and Their Outcomes International), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Exacerbations and Their Outcomes International (EXACOS International): Burden of Severe Exacerbations of COPD and the Association Between Frequency of Severe Exacerbations and Clinical and Health-care Utilization Outcomes
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence and correlates of breathlessness in adults: an umbrella review and updated systematic review with meta-analysis in general and clinical populations.European respiratory review : an official journal of the European Respiratory Society · 2025Pooled it
- Real-World Safety of Fluticasone Furoate/Umeclidinium/Vilanterol in Patients with Asthma or Chronic Obstructive Pulmonary Disease (COPD), and Clinical Outcomes in COPD: Post-marketing Surveillance in Korea.Tuberculosis and respiratory diseases · 2026Article
- Prognostic value of distance-saturation product in COPD: Korean nationwide cohort study.ERJ open research · 2026Article
- Prognostic value of gait speed for exacerbations and mortality in COPD.ERJ open research · 2026Article
- Integration of circulating tumor DNA data enhances lung cancer prediction in patients with COPD.Scientific reports · 2026Article
- Irisin, BMI, and SII as Predictors of Frequent Acute Exacerbations in COPD: Development of a Predictive Nomogram.International journal of chronic obstructive pulmonary disease · 2026Observational
- Clinical Characteristics of Individuals with Chronic Obstructive Pulmonary Disease (COPD), Pre-COPD, Smokers with Normal Lung Function in Korea: Updated Analysis of the Korea COPD Subgroup Study Cohort.Tuberculosis and respiratory diseases · 2026Article
- Beyond pathogens: a narrative review of the immunological nexus of damage-associated molecular patterns and inflammasome activation in sterile AECOPD.Frontiers in immunology · 2026Review
- Management of COPD With Cardiovascular Risk in Asia: A Review by the Asian Pacific Society of Respirology COPD Assembly.Respirology (Carlton, Vic.) · 2025Review
- Effects of Roflumilast on Exacerbations and Lung Function in COPD Patients with Bronchiectasis.Chonnam medical journal · 2025Article
- Impact of the COVID-19 Lockdown on Inhaler Adherence in Patients with COPD: A South Korean Nationwide Cohort Study.Healthcare (Basel, Switzerland) · 2025Article
- Association Between Urban Green Space and Acute Exacerbations of COPD in Korea: A Nationwide Study Using the NHIS-NSC Cohort.International journal of chronic obstructive pulmonary disease · 2025Article
- Risk factors for prolonged hospitalization as a marker for difficult-to-manage exacerbations of chronic obstructive lung disease (COPD): the DiMECO Study.BMC pulmonary medicine · 2024Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundAcute exacerbations of chronic obstructive pulmonary disease (AECOPD) exert a substantial burden on patients and healthcare systems; however, data related to the frequency of AECOPD in the Korean population are limited. Therefore, this study aimed to describe the frequency of severe, and moderate or severe AECOPD, as well as clinical and demographic characteristics of patients with chronic obstructive pulmonary disease (COPD) in South Korea.
methodsData from patients aged > 40 years with post-bronchodilator forced expiratory volume in 1 second (FEV
resultsData from 3,477 Korean patients (mean age, 68.5 years) with COPD were analyzed. Overall, most patients were male (92.3%), former or current smokers (90.8%), had a modified Medical Research Council dyspnea scale score ≥ 1 (83.3%), and had moderate airflow limitation (54.4%). The mean body mass index (BMI) of the study population was 23.1 kg/m², and 27.6% were obese or overweight. Hypertension was the most common comorbidity (37.6%). The mean blood eosinophil count was 226.8 cells/μL, with 21.9% of patients having ≥ 300 cells/μL. A clinically insignificant change in FEV
conclusionFindings from this Korean cohort of patients with COPD indicated a high exacerbation burden, which may be attributable to the unique characteristics of the study population and suboptimal disease management. This highlights the need to align clinical practices with the latest treatment recommendations to alleviate AECOPD burden in Korea.
trial registrationClinicalTrials.gov Identifier: NCT05750810.
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