Evidence map›Paper›PMID 38769641›Full record

ArticleJournal of veterinary internal medicine

Clinicopathological and diagnostic imaging findings in a dog with neurocandidiasis.

Emilie Royaux, Davide Corbetta, Monika Czerwiñska, Fiona Gosling, Marie-Aude Genain

Abstract readCase Reports
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Emilie RoyauxDavies Veterinary Specialists part of Linnaeus Veterinary Limited, Hitchin, United Kingdom.ORCID https://orcid.org/0009-0004-8463-3063
Davide CorbettaThe Queen's Veterinary Hospital, University of Cambridge, Cambridge, United Kingdom.
Monika CzerwiñskaDavies Veterinary Specialists part of Linnaeus Veterinary Limited, Hitchin, United Kingdom.
Fiona GoslingVeterinary Pathology Group (VPG), Hitchin, United Kingdom.
Marie-Aude GenainCambridge Veterinary School, Veterinary Medicine, Cambridge, United Kingdom.

Funding

Linnaeus Veterinary Limited supported the costs of the Open Access Publication Charges
6 · The paper itself

Abstract

Neurocandidiasis is systemic candidiasis with central nervous system involvement. This case report describes the clinical presentation, diagnostic test results, and histopathology of a dog with neurocandidiasis. A 3-year-old German shepherd dog was presented for a 3-day history of abnormal mentation, neck pain, and ataxia. Magnetic resonance imaging (MRI) scan of the brain revealed multifocal, small, round, intra-axial lesions within the forebrain. Examination of the cerebrospinal fluid revealed severe neutrophilic inflammation. Extensive testing for infectious diseases was negative. The dog was administered immunosuppressive doses of corticosteroids. The dog's clinical signs improved transiently but got worse 12 days after starting the treatment. Repeat MRI scan revealed multiple, intra-axial, target-like nodular lesions scattered throughout the brain parenchyma. In the temporal muscles, nodules were seen. Cytology of the fine needle aspirates of the nodules in the temporal muscles revealed a neutrophilic inflammation with hyalohyphomycosis. Postmortem examination was compatible with a severe systemic fungal infection. Candida albicans was isolated from the brain, kidney, and heart.

Indexed as

CandidiasisDog DiseasesMagnetic Resonance ImagingAnimalsAntifungal AgentsBrainCandida albicansCentral Nervous System Fungal InfectionsDogsFemaleMaleAntifungal AgentsCSF analysisfungalmicrobiologyneuroanatomy and neuropathologyneuroimagingneurology

Identifiers

PMID38769641
PMCPMC11256180

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.