ArticleCritical care (London, England)2024
Targeted temperature control following traumatic brain injury: ESICM/NACCS best practice consensus recommendations.
Article in Critical care (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Comparative Effectiveness of Different Targeted Temperature Management Modalities for Adult Patients with Traumatic Brain Injury.Neurocritical care · 2026Pooled it
- Guidelines for Enhanced Recovery After Trauma and Intensive Care (ERATIC): Enhanced Recovery After Surgery (ERAS) and International Association for Trauma Surgery and Intensive Care (IATSIC) Society Recommendations: Paper 2: Postoperative and Intensive Care Recommendations.World journal of surgery · 2025Guideline
- Intracranial multimodal monitoring in neurocritical care (Neurocore-iMMM): an open, decentralized consensus.Critical care (London, England) · 2024Guideline
- Impact of fever on the outcome non-anoxic acute brain injury patients: a systematic review and meta-analysis.Critical care (London, England) · 2024Pooled it
- Nanozyme-based therapeutic strategies for traumatic brain injury.International journal of pharmaceutics: X · 2026Review
- Functional near-infrared spectroscopy: Systematic mapping of abnormal brain function features in neurological disorders.Neural regeneration research · 2026Article
- Temperature control in acute brain injury.Intensive care medicine · 2026Review
- Application of GHOST-CAP strategy combined with multimodal monitoring in the treatment of a patient with polytrauma complicated by severe traumatic brain injury: a case report.Frontiers in medicine · 2026Article
- Influence of early temperature trajectories on clinical outcomes in traumatic brain injury: a multicenter validation study using machine learning.European journal of medical research · 2025Article
- Arctic Sun Surface Temperature Management Device for Neuroprotection During Pregnancy-A Short Case Report and Review of the Literature.Reports (MDPI) · 2025Article
- Harnessing hibernation: Unlocking nature's secrets for advances in healthy aging, critical care, and space exploration.Annals of the New York Academy of Sciences · 2025Review
- Traumatic brain injury in obstetric patients: challenges and management strategiesRevista colombiana de obstetricia y ginecologia · 2025Review
- Optimizing Vital Signs in Patients With Traumatic Brain Injury: Reinforcement Learning Algorithm Development and Validation.Journal of medical Internet research · 2025Article
- Association between traumatic brain injury and risk of developing infections in the central nervous system and periphery.Metabolic brain disease · 2025Review
- Effect of extended intravenous diclofenac infusions on brain tissue oxygenation in patients with acute brain injury.Intensive care medicine experimental · 2025Article
- Update on traumatic brain injury in the ICU.Current opinion in anaesthesiology · 2025Review
- Development and Validation of a Neuro-Intensive Care Protocol for Traumatic Brain Injury Management.Cureus · 2025Article
- Incidence and Current Status of Acute Management of Traumatic Brain Injuries in Korea: A National Population-Based Study of 2016-2018.Korean journal of neurotrauma · 2025Article
- Selective head-and-neck cooling as a treatment method for concussions in elite male rugby union players: the Clinical Observed Outcomes with Local HEad-and-neck cooling After Diagnosed concussions (COOLHEAD) study protocol.BMJ open sport & exercise medicine · 2025Article
- Advancements in the application of multimodal monitoring and machine learning for the development of personalized therapeutic strategies in traumatic brain injury.Frontiers in human neuroscience · 2025Review
Corrections and comments
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Authors and funding
21 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aims and scopeThe aim of this panel was to develop consensus recommendations on targeted temperature control (TTC) in patients with severe traumatic brain injury (TBI) and in patients with moderate TBI who deteriorate and require admission to the intensive care unit for intracranial pressure (ICP) management.
methodsA group of 18 international neuro-intensive care experts in the acute management of TBI participated in a modified Delphi process. An online anonymised survey based on a systematic literature review was completed ahead of the meeting, before the group convened to explore the level of consensus on TTC following TBI. Outputs from the meeting were combined into a further anonymous online survey round to finalise recommendations. Thresholds of ≥ 16 out of 18 panel members in agreement (≥ 88%) for strong consensus and ≥ 14 out of 18 (≥ 78%) for moderate consensus were prospectively set for all statements.
resultsStrong consensus was reached on TTC being essential for high-quality TBI care. It was recommended that temperature should be monitored continuously, and that fever should be promptly identified and managed in patients perceived to be at risk of secondary brain injury. Controlled normothermia (36.0-37.5 °C) was strongly recommended as a therapeutic option to be considered in tier 1 and 2 of the Seattle International Severe Traumatic Brain Injury Consensus Conference ICP management protocol. Temperature control targets should be individualised based on the perceived risk of secondary brain injury and fever aetiology.
conclusionsBased on a modified Delphi expert consensus process, this report aims to inform on best practices for TTC delivery for patients following TBI, and to highlight areas of need for further research to improve clinical guidelines in this setting.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.