ArticleNature methods2024
Metabuli: sensitive and specific metagenomic classification via joint analysis of amino acid and DNA.
Article in Nature methods, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Perseus: lineage-aware refinement of Kraken2 taxonomic classification for long read metagenomes.Bioinformatics (Oxford, England) · 2026Article
- Metagenome-assembled genomes for NMicrobiology resource announcements · 2026Article
- ViralQC: a tool for assessing completeness and contamination of predicted viral contigs.Bioinformatics (Oxford, England) · 2026Article
- Article
- Comprehensive taxonomic identification of microbial species in metagenomic data using SingleM and Sandpiper.Nature biotechnology · 2026Article
- A review of computational approaches for metagenomics by long-read sequencing.Science China. Life sciences · 2026Review
- TIPP-SD: A new method for species detection in microbiomes.PLoS computational biology · 2026Article
- LEMMIv2: benchmarking framework for metagenomic and 16S amplicon profilers with a catalogue of evaluated tools.Genome biology · 2026Article
- Improving metagenome binning by integrating intrinsic features and taxonomy.Nature biotechnology · 2026Article
- Article
- Reference-free k-mer based dissimilarity measures for metagenomes comparison.Frontiers in bioinformatics · 2026Article
- Machine Learning Enables Alignment-Free Distance Calculation and Phylogenetic Placement Using k-Mer Frequencies.Molecular ecology resources · 2025Article
- Evaluation of metagenome binning: advances and challenges.Briefings in bioinformatics · 2025Article
- The Role of Nucleotide Sequencing in Natural Product Drug Discovery.Journal of natural products · 2025Review
- Easy and interactive taxonomic profiling with Metabuli App.Bioinformatics (Oxford, England) · 2025Article
- A Comprehensive Evaluation of Taxonomic Classifiers in Marine Vertebrate eDNA Studies.Molecular ecology resources · 2025Article
- ganon2: up-to-date and scalable metagenomics analysis.NAR genomics and bioinformatics · 2025Article
- CAMI Benchmarking Portal: online evaluation and ranking of metagenomic software.Nucleic acids research · 2025Article
- Comparative metagenomics indicates metabolic niche differentiation of benthic and planktonic Woeseiaceae.Environmental microbiome · 2025Article
- Cutting-edge deep-learning based tools for metagenomic research.National science review · 2025Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Metagenomic taxonomic classifiers analyze either DNA or amino acid (AA) sequences. Metabuli ( https://metabuli.steineggerlab.com ), however, jointly analyzes both DNA and AA to leverage AA conservation for sensitive homology detection and DNA mutations for specific differentiation of closely related taxa. In the Critical Assessment of Metagenome Interpretation 2 plant-associated dataset, Metabuli covered 99% and 98% of classifications of state-of-the-art DNA- and AA-based classifiers, respectively.
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