Evidence map›Paper›PMID 38769329›Full record

ArticleScientific reports2024

Synthetic CT generation based on CBCT using improved vision transformer CycleGAN.

Yuxin Hu, Han Zhou, Ning Cao, Can Li, Can Hu

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Deep Learning for CT Synthesis in Radiotherapy.Bioengineering (Basel, Switzerland) · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuxin HuSchool of Computer and Software, Hohai University, Nanjing, 211100, China.
Han ZhouSchool of Electronic Science and Engineering, Nanjing University, NanJing, 210046, China.
Ning CaoSchool of Computer and Software, Hohai University, Nanjing, 211100, China.
Can LiEngineering Research Center of TCM Intelligence Health Service, School of Artificial Intelligence and Information Technology, Nanjing University of Chinese Medicine, Nanjing, 210023, China. lican@njucm.edu.cn.
Can HuSchool of Computer and Software, Hohai University, Nanjing, 211100, China. hucan@hhu.edu.cn.

Funding

Jiangsu Provincial Key Research and Development Program BE2020714
6 · The paper itself

Abstract

Cone-beam computed tomography (CBCT) is a crucial component of adaptive radiation therapy; however, it frequently encounters challenges such as artifacts and noise, significantly constraining its clinical utility. While CycleGAN is a widely employed method for CT image synthesis, it has notable limitations regarding the inadequate capture of global features. To tackle these challenges, we introduce a refined unsupervised learning model called improved vision transformer CycleGAN (IViT-CycleGAN). Firstly, we integrate a U-net framework that builds upon ViT. Next, we augment the feed-forward neural network by incorporating deep convolutional networks. Lastly, we enhance the stability of the model training process by introducing gradient penalty and integrating an additional loss term into the generator loss. The experiment demonstrates from multiple perspectives that our model-generated synthesizing CT(sCT) has significant advantages compared to other unsupervised learning models, thereby validating the clinical applicability and robustness of our model. In future clinical practice, our model has the potential to assist clinical practitioners in formulating precise radiotherapy plans.

Indexed as

Cone-Beam Computed TomographyNeural Networks, ComputerAlgorithmsHumansImage Processing, Computer-AssistedTomography, X-Ray ComputedUnsupervised Machine Learning

Identifiers

PMID38769329
PMCPMC11106312

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.