ArticleBiological cybernetics2024
A computational neural model that incorporates both intrinsic dynamics and sensory feedback in the Aplysia feeding network.
Article in Biological cybernetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Context-dependent mechanical reconfiguration is necessary for multifunctional behavior in an intrinsically confined hydrostat.iScience · 2026Article
- NEURONpyxl: fast, flexible, Python-integrated simulation of biophysical neural networks with complex plastic synapses.Frontiers in computational neuroscience · 2026Article
- Article
- Incorporating buccal mass planar mechanics and anatomical features improves neuromechanical modeling of Aplysia feeding behavior.Biological cybernetics · 2025Article
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Authors and funding
6 authors.
Funding
Abstract
Studying the nervous system underlying animal motor control can shed light on how animals can adapt flexibly to a changing environment. We focus on the neural basis of feeding control in Aplysia californica. Using the Synthetic Nervous System framework, we developed a model of Aplysia feeding neural circuitry that balances neurophysiological plausibility and computational complexity. The circuitry includes neurons, synapses, and feedback pathways identified in existing literature. We organized the neurons into three layers and five subnetworks according to their functional roles. Simulation results demonstrate that the circuitry model can capture the intrinsic dynamics at neuronal and network levels. When combined with a simplified peripheral biomechanical model, it is sufficient to mediate three animal-like feeding behaviors (biting, swallowing, and rejection). The kinematic, dynamic, and neural responses of the model also share similar features with animal data. These results emphasize the functional roles of sensory feedback during feeding.
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Registered trials
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