ArticleTranslational vision science & technology2024
Diurnal Variation in Choroidal Parameters Among Healthy Subjects Using Wide-Field Swept-Source Optical Coherence Tomography Angiography.
Article in Translational vision science & technology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Widefield optical coherence tomography angiography of fellow eyes in patients with Coats Disease.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Influence of Refraction on Widefield Retinal and Choroidal Vascular Metrics in Optical Coherence Tomography Angiography in a Caucasian Population.Translational vision science & technology · 2026Article
- Structural and vascular characteristics of PHOMS in pediatric pseudopapilledema.BMC ophthalmology · 2026Article
- Physical Activity and Macular Choroidal Circulation in Older Adults With Primary Open-Angle Glaucoma: A Swept-Source Optical Coherence Tomography Angiography Study.Translational vision science & technology · 2026Article
- Evaluation of retinochoroidal changes after implantable collamer lens implantation: insights from UWF-SS-OCTA and AI-based 3D modeling.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Investigating the Correlation Between Choroidal Alteration and Visual Function Metrics in Dysthyroid Optic Neuropathy.Translational vision science & technology · 2026Article
- Widefield Analysis of Choroidal Vascular Characteristics in Central Serous Chorioretinopathy With Different Choroidal Vein Drainage System.Translational vision science & technology · 2026Article
- Three-dimensional choroidal vessels assessment in age-related macular degeneration: a follow-up study.Eye (London, England) · 2026Article
- Ultra-widefield OCTA assessment of retinal and choroidal microcirculation in cerebral small vessel disease.Scientific reports · 2026Article
- Choroidal Vascular Remodeling and Retinal Response After Aflibercept Loading in Diabetic Macular Edema.Ophthalmology science · 2026Article
- Retinal and choroidal vascular density alterations in patients with schizophrenia: assessment via optical coherence tomography angiography.BMC psychiatry · 2026Article
- Microvascular and Ultrastructural Changes of the Retina and Choroid in Patients with Sickle Cell Anemia.Turkish journal of ophthalmology · 2025Article
- Comprehensive Visualization of Choroidal Alterations in Thyroid Eye Disease With Ultra-Widefield OCT Angiography.Investigative ophthalmology & visual science · 2025Article
- Choroid vascular index in myopic patients - A mini review.Taiwan journal of ophthalmologyReview
- Comparison of Choroidal Vascular Index Measurements in Pachychoroid Pigment Epitheliopathy using Manual ImageJ-Based Niblack and Protocol-Standardized Otsu Thresholding.Journal of current ophthalmologyArticle
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Authors and funding
9 authors.
Funding
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Abstract
Purpose: The purpose of this study was to evaluate the diurnal variation in choroidal parameters in a wide field area among healthy subjects and to identify correlations between choroidal luminal area and stromal area and various systemic factors. Methods: In this cross-sectional study, 42 eyes from 21 healthy participants (mean age = 32.4 ± 8.8 years) were examined using wide-field swept-source optical coherence tomography angiography (WF SS-OCTA, 24 mm × 20 mm). Measurements of choroidal parameters, including choroidal volume (CV), choroidal thickness (CT), choroidal vessel volume (CVV), and choroidal stromal volume (CSV), were taken at 8:00, 12:00, 18:00, and 22:00. Systemic factors, such as blood pressure and heart rate, were concurrently monitored. Results: Our study observed significant diurnal variations in the mean total CV, CT, CVV, and CSV, with minimum measurements around 12:00 (P < 0.001) and peak values at 22:00 (P < 0.001). Furthermore, changes in CV in specific regions were more closely associated with fluctuations in CVV than CSV in the same regions. No significant diurnal variations were found in systolic (P = 0.137) or diastolic blood pressure (P = 0.236), whereas significant variations were observed in the heart rate (P = 0.001). Conclusions: Our study reveals diurnal variations in choroidal parameters and their associations, emphasizing that changes in choroidal volume relate more to the luminal than the stromal area in vessel-rich regions. This enhances our understanding of choroidal-related ocular diseases. Translational Relevance: Regions with higher choroidal vasculature observed greater choroidal volume changes.
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