Evidence map›Paper›PMID 38767780›Full record

ArticleInfectious diseases and therapy2024

The Multifaceted Burden of Respiratory Syncytial Virus (RSV) Infections in Young Children on the Family: A European Study.

Ilona Trautmannsberger, Barbara Plagg, Ina Adamek, Silke Mader, Daniele de Luca, Susanna Esposito, Sven Arne Silfverdal, Luc J I Zimmermann, Christina Tischer, ResQ Family study group

Registry-linked trialAbstract read
In one paragraph

Article in Infectious diseases and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05550545 (ResQ Family), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05550545 unknown statusnot on this map

ResQ Family: Impact of Respiratory Syncytial Virus (RSV) Hospitalisation on Quality of Life of Families - A Multi-Country Study

TypeobservationalSponsorGlobal Foundation for the Care of Newborn InfantsRan2022 to 2024Enrolled120ConditionsRSV Infection, Quality of Life, Infant ALL, Caregiver BurdenArmscohort study
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Observational
  2. Article
  3. Transient tachypnoea: new concepts on the commonest neonatal respiratory disorder.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ilona TrautmannsbergerEuropean Foundation for the Care of Newborn Infants (EFCNI), Hofmannstraße 7a, 81379, Munich, Germany.ORCID http://orcid.org/0000-0002-9996-6117
Barbara PlaggInstitute of General Practice and Public Health, Provincial College for Health Professions Claudiana, 39100, Bolzano, Italy.ORCID http://orcid.org/0000-0002-6116-7504
Ina AdamekEuropean Foundation for the Care of Newborn Infants (EFCNI), Hofmannstraße 7a, 81379, Munich, Germany.ORCID http://orcid.org/0009-0004-9614-1058
Silke MaderEuropean Foundation for the Care of Newborn Infants (EFCNI), Hofmannstraße 7a, 81379, Munich, Germany. s.maderoffice@efcni.org.ORCID http://orcid.org/0000-0002-3396-0177
Daniele de LucaDivision of Pediatrics and Neonatal Critical Care, A. Béclère Medical Center, Paris Saclay University Hospitals, APHP, Paris, France.ORCID http://orcid.org/0000-0002-1639-9138
Susanna EspositoPaediatric Clinic, Pietro Barilla Children's Hospital, University of Parma, Parma, Italy.
Sven Arne SilfverdalDepartment of Clinical Sciences, Pediatrics, Umeå University, Umeå, Sweden.
Luc J I ZimmermannEuropean Foundation for the Care of Newborn Infants (EFCNI), Hofmannstraße 7a, 81379, Munich, Germany.ORCID http://orcid.org/0000-0002-1409-3821
Christina TischerEuropean Foundation for the Care of Newborn Infants (EFCNI), Hofmannstraße 7a, 81379, Munich, Germany.ORCID http://orcid.org/0000-0001-6699-9484
ResQ Family study group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSince the majority of hospitalisations due to RSV occur in young children, the illness profoundly influences the entire family. However, comprehensive evidence regarding its overall effects remains limited. The ResQ Family study aims to investigate the burden of RSV-induced pediatric hospitalisation on affected families.

methodsSpanning the 2022-2023 RSV season, an interdisciplinary, observational study was conducted in Germany, France, Italy and Sweden. Using an online questionnaire, parents and caregivers of children (< 24 months of age) with an RSV-induced hospitalisation were recruited. Information was gathered on topics related to RSV and parental health-related quality of life (HRQoL) during the acute infection phase (t0) and 6 weeks later (t1). Descriptive evaluations of the data set were performed during t0 and regarding a potential change over the observation period (t0 vs. t1). Subgroup analysis aimed to further identify differences across the countries.

resultsA total set of 138 affected parents/caregivers were included in the study, with 59 participants responding to the follow-up survey (t1). Particularly during the acute infection phase, parental HRQoL was shown to be negatively influenced by the child's RSV infection [total score (p < 0.001, d = 0.54), parent HRQoL summary score (p < 0.001, d = 0.67) and family functioning summary score (p = 0.007, d = 0.33)]. Significant disparities in disease awareness and support structures were observed across Europe, with France and Sweden showing notably higher levels.

conclusionThe ResQ Family study provides convincing evidence that RSV-associated hospitalisations in young children across Europe generate a multifaced burden for the entire family, partly even beyond the acute infection phase. Standardised approaches for disease prevention at societal, educational and policy levels are needed to guarantee every newborn the best possible start into life.

trial registrationClinicalTrials.gov, identifier, NCT05550545.

Indexed as

ChildrenDisease burdenFamilyHRQoLParentsQuality of lifeRespiratory syncytial virus (RSV)

Identifiers

PMID38767780
PMCPMC11219685

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.