Evidence map›Paper›PMID 38767760›Full record

ReviewCurrent heart failure reports2024

Sex-based Differences in Heart Failure Biomarkers.

Ainhoa Robles-Mezcua, Nelsa González Aguado, Antonia Pilar Martin de la Rosa, Concepción Cruzado-Álvarez, Clara Jiménez Rubio, Alejandro IPérez Cabeza, Juan José Gómez-Doblas, Manuel F Jiménez-Navarro, Mora Murri Pierri, José M García-Pinilla

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current heart failure reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ainhoa Robles-MezcuaÁrea del Corazón, Hospital Universitario Virgen de La Victoria, Málaga, Spain.
Nelsa González AguadoÁrea del Corazón, Hospital Universitario Virgen de La Victoria, Málaga, Spain.
Antonia Pilar Martin de la RosaÁrea del Corazón, Hospital Universitario Virgen de La Victoria, Málaga, Spain.
Concepción Cruzado-ÁlvarezÁrea del Corazón, Hospital Universitario Virgen de La Victoria, Málaga, Spain.
Clara Jiménez RubioÁrea del Corazón, Hospital Universitario Virgen de La Victoria, Málaga, Spain.
Alejandro IPérez CabezaÁrea del Corazón, Hospital Universitario Virgen de La Victoria, Málaga, Spain.
Juan José Gómez-DoblasÁrea del Corazón, Hospital Universitario Virgen de La Victoria, Málaga, Spain.
Manuel F Jiménez-NavarroÁrea del Corazón, Hospital Universitario Virgen de La Victoria, Málaga, Spain.
Mora Murri PierriÁrea del Corazón, Hospital Universitario Virgen de La Victoria, Málaga, Spain. moramurri@gmail.com.
José M García-PinillaÁrea del Corazón, Hospital Universitario Virgen de La Victoria, Málaga, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewDifferences in HF biomarker levels by sex may be due to hormonal, genetic, and fat distribution differences. Knowledge of these differences is scarce, and it is not well established whether they may affect their usefulness in the management of HF. RECENT

findingsThe different biomarker profiles in women and men have been confirmed in recent studies: in women, markers of cardiac stretch and fibrosis (NP and galectin-3) are higher, whereas in men, higher levels of markers of cardiac injury and inflammation (cTn and sST2) are found. The use of new biomarkers, together with growing evidence that a multimarker approach can provide better risk stratification, raises the question of building models that incorporate sex-specific diagnostic criteria. More and more research are being devoted to understanding sex-related differences in HF. The aim of this review is to review the dynamics of HF biomarkers according to sex and in different situations, to learn whether these sex differences may affect their use in the diagnosis and follow-up of HF patients.

Indexed as

BiomarkersHeart FailureFemaleHumansMaleSex FactorsBiomarkersBiomarkersHeart failureSex differences

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.