Evidence map›Paper›PMID 38767672›Full record

ReviewNaunyn-Schmiedeberg's archives of pharmacology2024

Systematic appraisals of naturally occurring alkaloids from medicinal plants.

Oluwole Solomon Oladeji, Kehinde Abraham Odelade, Ahmed Mahal, Ahmad J Obaidullah, Rahadian Zainul

Abstract readReview
PubMed Publisher
In one paragraph

Review in Naunyn-Schmiedeberg's archives of pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Merits of bioactivity and products ofFrontiers in plant science · 2026
    Pooled it
  2. Review
  3. Indole derivatives intervene osteoporosis via gut-bone axis.Frontiers in cellular and infection microbiology · 2026
    Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Oluwole Solomon OladejiNatural Products Research Unit, Department of Physical Sciences, College of Pure and Applied Sciences, Landmark University, Omu-Aran, PMB 1001, Nigeria.
Kehinde Abraham OdeladeDepartment of Science Laboratory Technology, Federal Polytechnic, Ayede, Ogbomoso, Nigeria.
Ahmed MahalDepartment of Medical Biochemical Analysis, College of Health Technology, Cihan University-Erbil, Erbil, Kurdistan Region, Iraq.
Ahmad J ObaidullahDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, 11451, Riyadh, Saudi Arabia.
Rahadian ZainulDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Negeri Padang, Padang, Indonesia. rahadianzmsiphd@fmipa.unp.ac.id.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alkaloids are a complex class of biologically active compounds with a broad spectrum of health-related applications. Particularly the alkaloids of indole, steroidal, terpenoids, isoquinoline, and bisbenzylisoquinoline have been extensively investigated. Ultimately, substantial advancement has been highlighted in the investigation of chemical constituents and the therapeutic benefits of plant alkaloids, particularly during the last ten years. A total of 386 alkaloids have been isolated from over 40 families, including Apocynaceae, Annonaceae, Rubiaceae, Menispermaceae, Ranunculaceae, Buxaceae, Papaveraceae, Magnoliaceae, Rutaceae and Phyllanthaceae. This paper will investigate several alkaloids that have been isolated from botanical medicines as well as offer an in-depth analysis of their cytotoxic properties.

Indexed as

AlkaloidsPlants, MedicinalAnimalsAntineoplastic Agents, PhytogenicHumansAlkaloidsAntineoplastic Agents, PhytogenicAlkaloidsBioactive compoundsBisbenzylisoquinolineCytotoxicityIndoleIsoquinolineTherapeutic benefits

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.