Evidence map›Paper›PMID 38767621›Full record

ArticleThe Journal of cell biology2024

WW domains: A globular NLS recognized by importin-α.

Natalia Elisa Bernardes, Yuh Min Chook

Abstract readComment
In one paragraph

Article in The Journal of cell biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Natalia Elisa BernardesDepartment of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Yuh Min ChookDepartment of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0002-4974-0726

Funding

Biochemical and cellular functions of Karyopherins - Revision - 2R35GM141461 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI Yuh Min Chook · 2021 to 2026
$2.8M
Alfred and Mabel Gilman Chair in Molecular PharmacologyEugene McDermott Scholar in Biomedical ResearchNIGMS NIH HHS R35 GM141461NIGMS NIH HHS R35GM141461Welch Foundation I-1532
6 · The paper itself

Abstract

In this issue, the discovery by Yang et al. (https://doi.org/10.1083/jcb.202308013) that folded WW domains of YAP1 and other proteins bind to Impα introduces a new class of globular NLS, contrasting with the extensively studied linear NLS motifs. This finding underscores the versatility of importins in recognizing their cargo proteins.

Indexed as

Nuclear Localization SignalsAdaptor Proteins, Signal Transducingalpha KaryopherinsHumansProtein BindingTranscription FactorsWW DomainsYAP-Signaling ProteinsAdaptor Proteins, Signal Transducingalpha KaryopherinsNuclear Localization SignalsTranscription FactorsYAP1 protein, humanYAP-Signaling Proteins

Identifiers

PMID38767621
PMCPMC11104269

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.