ArticlePsychiatry and clinical psychopharmacology2022
A Cross-Sectional Measurement of Endogenous Oxidative Stress Marker Levels in Obsessive Compulsive Disorder.
Article in Psychiatry and clinical psychopharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Heart rate dynamics and antioxidant capacity under cognitive-emotional load in obsessive-compulsive disorder.BMC psychiatry · 2026Article
- Micronutrient-immune interactions in mood and psychotic disorders: a case-control study of vitamin C, iron, zinc, magnesium, and peripheral blood cell indices.Scientific reports · 2026Article
- A Diagnosis Model of Typhoon-Related Post-Traumatic Stress Disorder Based on Fixel-Based Analysis in Machine Learning.Brain and behavior · 2026Article
- Choroidal Vascularity Index in Schizophrenia Compared to Healthy Subjects: A Cross-Sectional Study.Health science reports · 2026Article
- Differences in brain functioning between obsessive-compulsive disorder and generalized anxiety disorder: a clinical study using functional near-infrared spectroscopy.Frontiers in psychiatry · 2026Article
- Interactive Effect of Plasma Lipidome on Neuropsychiatric Disorders: A Bidirectional Mendelian Randomization Study.Molecular neurobiology · 2025Article
- Characterization of Genetic and Chemical Drivers in the Pathogenesis of DRESS Syndrome: In Silico Study.Health science reports · 2025Article
- Differential Expression of miR-26b-5p, EGR1, and STAT1 in Peripheral Blood of Schizophrenia Patients.Psychiatry and clinical psychopharmacology · 2024Article
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Authors and funding
5 authors.
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Abstract
Background: There is a correlation between the increase in reactive oxygen radicals and the presence of specific mental illnesses. In this context, the objective of this study is to investigate the relationship between obsessive-compulsive disorder and the variations in the levels of several endogenous oxidative stress markers. Methods: Thirty obsessive-compulsive disorder patients were included in the study as the patient group, and 30 healthy volunteers of matching demographic characteristics were included in the study as the control group. Accordingly, the patient group consisted of 10 females and 20 males with a mean age of 29.5 ± 6.1 years, and the control group consisted of 15 females and 15 males with a mean age of 31.9±5.6 years. The serum nicotinamide adenine dinucleotide phosphate oxidase-2, nicotinamide adenine dinucleotide phosphate oxidase-4, and malondialdehyde levels of the 2 groups were compared using the independent samples Results: The serum nicotinamide adenine dinucleotide phosphate oxidase-2, nicotinamide adenine dinucleotide phosphate oxidase-4, and malondialdehyde levels of the patient group were statistically significantly higher than those of the control group ( Conclusion: The results of this study indicated that oxidative stress and lipid peroxidation levels were higher in obsessive-compulsive disorder patients. Based on this finding, NOX-2 and NOX-4 levels can be used as indicators of endogenous oxidative stress in obsessive-compulsive disorder patients.
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