Evidence map›Paper›PMID 38766477›Full record

ArticleTherapeutic advances in gastroenterology2024

Impact of inflammatory bowel disease on women's reproductive life: a questionnaire-based study.

Fabiana Zingone, Alessandro Borsato, Daria Maniero, Francesco Della Loggia, Greta Lorenzon, Annalisa Zanini, Cristina Canova, Brigida Barberio, Edoardo Vincenzo Savarino

Abstract read
In one paragraph

Article in Therapeutic advances in gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fabiana ZingoneGastroenterology Unit, Department of Surgery, Oncology and Gastroenterology, University of Padua, Via Giustiniani 2, Padua 235128, Italy.ORCID https://orcid.org/0000-0003-1133-1502
Alessandro BorsatoGastroenterology Unit, Azienda Ospedale Università Padova, Padova, Italy.
Daria ManieroDepartment of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy.
Francesco Della LoggiaDepartment of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy.
Greta LorenzonDepartment of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy.
Annalisa ZaniniDepartment of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy.
Cristina CanovaUnit of Biostatistics, Epidemiology and Public Health, Department of Cardio-Thoraco-Vascular Sciences and Public Health, University of Padua, Padua, Italy.
Brigida BarberioGastroenterology Unit, Azienda Ospedale Università Padova, Padova, Italy.ORCID https://orcid.org/0000-0002-3164-8243
Edoardo Vincenzo SavarinoDepartment of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy.ORCID https://orcid.org/0000-0002-3187-2894

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Inflammatory bowel diseases (IBDs) have a peak incidence between the second and fourth decades of life and can affect women's reproductive life. Objectives: Our study aimed to assess the impact of IBD on the reproductive life of female patients with this condition. Design: Cross-sectional study. Methods: Women with IBD followed at our IBD Unit and a group of healthy controls were enrolled. Data on reproductive life were collected using a dedicated questionnaire. Results: The study included 457 women, of whom 228 had IBD, and 229 age-matched healthy controls. No differences were found in the use of contraceptives, infertility, and endometriosis. The risk of spontaneous and voluntary abortions was significantly higher in IBD patients than in healthy controls [odds ratio (OR) 2 and 3.62, respectively]. The risk of obstetrical complications in the IBD population was more than six times higher in patients who experienced disease reactivations during pregnancy than in those with persistent remission [OR 6.9, 95% confidence interval (CI) 1.51-31.28]. Finally, we found that the chances of breastfeeding were 66% lower in patients with IBD than in controls (OR 0.44, 95% CI 0.22-0.91). Conclusion: Our study underlines the negative impact of IBD on women's reproductive life, supporting the need for proactive preconception counseling.

Indexed as

breastfeedingdiseasefertilityinflammatory bowel diseasepregnancywomen

Identifiers

PMID38766477
PMCPMC11102668

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.