Evidence map›Paper›PMID 38766222›Full record

ArticlebioRxiv : the preprint server for biology2024

Identification of Fasnall as a therapeutically effective Complex I inhibitor.

Dzmitry Mukha, Jena Dessain, Seamus O'Connor, Katherine Pniewski, Fabrizio Bertolazzi, Jeet Patel, Mary Mullins, Zachary T Schug

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dzmitry MukhaMolecular and Cellular Oncogenesis Program, Ellen and Ronald Caplan Cancer Center, The Wistar Institute, Philadelphia, PA, United States.ORCID 0000-0003-3027-6270
Jena DessainMolecular and Cellular Oncogenesis Program, Ellen and Ronald Caplan Cancer Center, The Wistar Institute, Philadelphia, PA, United States.
Seamus O'ConnorMolecular and Cellular Oncogenesis Program, Ellen and Ronald Caplan Cancer Center, The Wistar Institute, Philadelphia, PA, United States.ORCID 0000-0001-7147-0008
Katherine PniewskiMolecular and Cellular Oncogenesis Program, Ellen and Ronald Caplan Cancer Center, The Wistar Institute, Philadelphia, PA, United States.ORCID 0000-0002-6754-3814
Fabrizio BertolazziMolecular and Cellular Oncogenesis Program, Ellen and Ronald Caplan Cancer Center, The Wistar Institute, Philadelphia, PA, United States.ORCID 0000-0003-2121-1272
Jeet PatelDepartment of Cell & Developmental Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.ORCID 0000-0002-0214-4484
Mary MullinsDepartment of Cell & Developmental Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.ORCID 0000-0002-9979-1564
Zachary T SchugMolecular and Cellular Oncogenesis Program, Ellen and Ronald Caplan Cancer Center, The Wistar Institute, Philadelphia, PA, United States.ORCID 0000-0003-4197-8227

Funding

Tumor Microenvironment and MetastasisP30CA010815 · NCI · WISTAR INSTITUTE · PI Luis J Montaner · 1985 to 2026
$75.9M
Targeting the MAP and PI3 Kinase Pathways in MelanomaP01CA114046 · NCI · WISTAR INSTITUTE · PI AMARAVADI, RAVI K · 2008 to 2023
$37.1M
The multifaceted role of acetate in cancerDP2CA249950 · NCI · WISTAR INSTITUTE · PI SCHUG, ZACHARY T · 2019 to 2019
$2.7M
Purchase of a Q Exactive HF mass spectrometer system for metabolomicsS10OD023586 · OD · WISTAR INSTITUTE · PI SPEICHER, DAVID W. · 2017 to 2017
$600k
NCI NIH HHS DP2 CA249950NCI NIH HHS P01 CA114046NCI NIH HHS P30 CA010815NIH HHS S10 OD023586
6 · The paper itself

Abstract

Proliferating cancer cells actively utilize anabolic processes for biomass production, including

Identifiers

PMID38766222
PMCPMC11100613

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.