Evidence map›Paper›PMID 38766185›Full record

ArticlebioRxiv : the preprint server for biology2024

mRNA psi profiling using nanopore DRS reveals cell type-specific pseudouridylation.

Caroline A McCormick, Michele Meseonznik, Yuchen Qiu, Oleksandra Fanari, Mitchell Thomas, Yifang Liu, Dylan Bloch, Isabel N Klink, Miten Jain, Meni Wanunu and 1 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Caroline A McCormickDept. of Bioengineering, Northeastern University, Boston, MA.ORCID 0009-0000-0670-6707
Michele MeseonznikDept. of Bioengineering, Northeastern University, Boston, MA.
Yuchen QiuDept. of Bioengineering, Northeastern University, Boston, MA.ORCID 0009-0001-1544-9682
Oleksandra FanariDept. of Bioengineering, Northeastern University, Boston, MA.ORCID 0009-0003-2915-859X
Mitchell ThomasDept. of Bioengineering, Northeastern University, Boston, MA.
Yifang LiuDept. of Bioengineering, Northeastern University, Boston, MA.
Dylan BlochDept. of Bioengineering, Northeastern University, Boston, MA.ORCID 0000-0002-5382-5765
Isabel N KlinkDept. of Bioengineering, Northeastern University, Boston, MA.ORCID 0009-0002-9567-8158
Miten JainDept. of Bioengineering, Northeastern University, Boston, MA.ORCID 0000-0002-4571-3982
Meni WanunuDept. of Bioengineering, Northeastern University, Boston, MA.ORCID 0000-0002-9837-0004
Sara H RouhanifardDept. of Bioengineering, Northeastern University, Boston, MA.ORCID 0000-0002-6991-4877

Funding

Technology Development Coordinating CenterU24HG011735 · NHGRI · JACKSON LABORATORY · PI Mark D ADAMS · 2021 to 2026
$8.1M
Synthetic mRNA Control Set for Nanopore-Based Pseudouridine Modification Profiling in Human TranscriptomesR01HG012856 · NHGRI · NORTHEASTERN UNIVERSITY · PI Sara Hakim Rouhanifard · 2023 to 2026
$3.4M
Single-cell direct RNA sequencing using electrical zero-mode waveguides and engineered reverse transcriptasesR01HG011087 · NHGRI · NORTHEASTERN UNIVERSITY · PI WANUNU, MENI · 2020 to 2023
$3.0M
NHGRI NIH HHS R01 HG011087NHGRI NIH HHS R01 HG012856NHGRI NIH HHS U24 HG011735
6 · The paper itself

Abstract

Pseudouridine (psi) is one of the most abundant human mRNA modifications generated via psi synthases, including

Identifiers

PMID38766185
PMCPMC11100687

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.